I take Desloratadine, an antihistamine for the itching and it works great. For dry skin on the feet, I use Urea Cream. I rotate using various creams/lotions for dry skin but always come back to Cetaphil lotion. I take HU, 500 mg 4x week. Dry skin and dry eyes are my main issues. I use Refresh over the counter for my eyes, along with Restasis. Managing okay at age 71. I've been ET/Jak2 for 2 years.