Superoxidized water (aka pure hypochlorous solution)?

Posted by lvnl @lvnl, Dec 10 9:30pm

Anyone know anything about superoxidized water (aka pure hypochlorous solution)? I got a steam evaporative humidifier which is supposed to be safe for us because the water, of course, is boiled before it's aerosolized. The cleaning is less onerous than with the "cold" humidifiers which have filters that accumulate bacteria and get gross etc. But you are supposed to keep it clean. The brand (Boneco) sells its own cleaner additive which is just citric acid.
I discovered claims that superoxidized water aka hypochlorous solution is a nontoxic antimicrobial, used in various formulations found in drug stores and apparently used in hospitals. It is approved by the American Hospital Association. It can be used as an additive in the humidifier tank and is supposed to be safe for COPD patients so I imagine that would apply to us too.
Anybody have experience or insights? Thanks in advance!

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ok, I became interested and picked this review :

Yan, P.; Daliri, E.B.; Oh,D.-H. New Clinical Applications of
Electrolyzed Water: A Review. Microorganisms 2021, 9, 136.
https://doi.org/10.3390/
9. Conclusions
Electrolyzed water (EW) is an effective disinfectant, with several advantages such as on-the-spot,
cheap, environmentally friendly and safety production. Nowadays, with the development of a
novel popular type of slightly acid electrolyzed water (SAEW) some limitations have been resolved.
It has been reported that SAEW does not irritate the hands, skin, and mucous membranes,
and causes no safety issues from Cl2off-gassing.
It recently emerged with great potential for clinical applications.
However, the antimicrobial effect of EW is influenced by the presence of organic matter,
water pollutants, and the hardness of the product. Therefore, a dynamic and advanced EW
production system or the hurdle technology of cobing with multiple technologies-based
EW that are able to overcome currently limitations. These may expand the use of EW in
clinical applications.

REPLY
@bsi15

ok, I became interested and picked this review :

Yan, P.; Daliri, E.B.; Oh,D.-H. New Clinical Applications of
Electrolyzed Water: A Review. Microorganisms 2021, 9, 136.
https://doi.org/10.3390/
9. Conclusions
Electrolyzed water (EW) is an effective disinfectant, with several advantages such as on-the-spot,
cheap, environmentally friendly and safety production. Nowadays, with the development of a
novel popular type of slightly acid electrolyzed water (SAEW) some limitations have been resolved.
It has been reported that SAEW does not irritate the hands, skin, and mucous membranes,
and causes no safety issues from Cl2off-gassing.
It recently emerged with great potential for clinical applications.
However, the antimicrobial effect of EW is influenced by the presence of organic matter,
water pollutants, and the hardness of the product. Therefore, a dynamic and advanced EW
production system or the hurdle technology of cobing with multiple technologies-based
EW that are able to overcome currently limitations. These may expand the use of EW in
clinical applications.

Jump to this post

@lvnl and @bsi15, thank you so much for this very useful info!
best wishes of great health to us all!

REPLY
@bsi15

ok, I became interested and picked this review :

Yan, P.; Daliri, E.B.; Oh,D.-H. New Clinical Applications of
Electrolyzed Water: A Review. Microorganisms 2021, 9, 136.
https://doi.org/10.3390/
9. Conclusions
Electrolyzed water (EW) is an effective disinfectant, with several advantages such as on-the-spot,
cheap, environmentally friendly and safety production. Nowadays, with the development of a
novel popular type of slightly acid electrolyzed water (SAEW) some limitations have been resolved.
It has been reported that SAEW does not irritate the hands, skin, and mucous membranes,
and causes no safety issues from Cl2off-gassing.
It recently emerged with great potential for clinical applications.
However, the antimicrobial effect of EW is influenced by the presence of organic matter,
water pollutants, and the hardness of the product. Therefore, a dynamic and advanced EW
production system or the hurdle technology of cobing with multiple technologies-based
EW that are able to overcome currently limitations. These may expand the use of EW in
clinical applications.

Jump to this post

bsi15, when I click on the above link, I get an error, not found message. Could you please post the entire link? Thanks

REPLY
@lvnl

Interesting! Thank you!

Jump to this post

The concern I have is VERY short shelf life of hypochlorous solutions - like 48 hours. Labs and facilities that use it make their own on the spot Also it would be hard to know the concentration required
See this study:
https://johnes.org/wp-content/uploads/2021/02/LeDantec_Chlorine_v_mycobacteria_AEM-2002.pdf

REPLY

Might be a question for Dr. Falkinham. He's often active on the NTMinfo.org website and answers questions people post about water and safety.

REPLY
@sueinmn

The concern I have is VERY short shelf life of hypochlorous solutions - like 48 hours. Labs and facilities that use it make their own on the spot Also it would be hard to know the concentration required
See this study:
https://johnes.org/wp-content/uploads/2021/02/LeDantec_Chlorine_v_mycobacteria_AEM-2002.pdf

Jump to this post

Thanks Sue, I'm afraid I need a translation for that study. I think it's saying a lot of microbacteria are resistant to chlorine but is hypochlorous solution the same as the commonly used chlorine? Or do different formulations not matter? I've bought a Purefy brand humidifier additive which is a hypochlorous solution & was looking to see exactly whether it's available to just dilute myself since the product is expensive. But as you say, I don't find anything about proportions. The Purefy company doesn't say anything about very short shelf life (what I bought would last at least a month). But then, the info they make available is very limited which isn't so reassuring either. So I'm hitting a wall at this point. Maybe Dr Falkinham as Scoop suggests!

REPLY
@bsi15

ok, I became interested and picked this review :

Yan, P.; Daliri, E.B.; Oh,D.-H. New Clinical Applications of
Electrolyzed Water: A Review. Microorganisms 2021, 9, 136.
https://doi.org/10.3390/
9. Conclusions
Electrolyzed water (EW) is an effective disinfectant, with several advantages such as on-the-spot,
cheap, environmentally friendly and safety production. Nowadays, with the development of a
novel popular type of slightly acid electrolyzed water (SAEW) some limitations have been resolved.
It has been reported that SAEW does not irritate the hands, skin, and mucous membranes,
and causes no safety issues from Cl2off-gassing.
It recently emerged with great potential for clinical applications.
However, the antimicrobial effect of EW is influenced by the presence of organic matter,
water pollutants, and the hardness of the product. Therefore, a dynamic and advanced EW
production system or the hurdle technology of cobing with multiple technologies-based
EW that are able to overcome currently limitations. These may expand the use of EW in
clinical applications.

Jump to this post

https://www.mdpi.com/2076-2607/9/1/136/pdf
from 2021 , 19 pages .pdf ,
cited by 101 :
https://scholar.google.de/scholar?cites=14308069027946168969&as_sdt=2005&sciodt=0,5&hl=de
found with keyword search at google scholar
The CDC-guidelines are from 2008
I found no suitable guidelines at WHO

REPLY
@lvnl

Thanks Sue, I'm afraid I need a translation for that study. I think it's saying a lot of microbacteria are resistant to chlorine but is hypochlorous solution the same as the commonly used chlorine? Or do different formulations not matter? I've bought a Purefy brand humidifier additive which is a hypochlorous solution & was looking to see exactly whether it's available to just dilute myself since the product is expensive. But as you say, I don't find anything about proportions. The Purefy company doesn't say anything about very short shelf life (what I bought would last at least a month). But then, the info they make available is very limited which isn't so reassuring either. So I'm hitting a wall at this point. Maybe Dr Falkinham as Scoop suggests!

Jump to this post

Sorry I attached the wrong link - I have to go back and find the other one.

Here is the one I meant to use:
https://www.cdc.gov/infection-control/hcp/disinfection-sterilization/chemical-disinfectants.html
And here is the pertinent text:
"The microbicidal activity of a new disinfectant, "superoxidized water," has been examined The concept of electrolyzing saline to create a disinfectant or antiseptics is appealing because the basic materials of saline and electricity are inexpensive and the end product (i.e., water) does not damage the environment. The main products of this water are hypochlorous acid (e.g., at a concentration of about 144 mg/L) and chlorine. As with any germicide, the antimicrobial activity of superoxidized water is strongly affected by the concentration of the active ingredient (available free chlorine) 536. One manufacturer generates the disinfectant at the point of use by passing a saline solution over coated titanium electrodes at 9 amps. The product generated has a pH of 5.0–6.5 and an oxidation-reduction potential (redox) of >950 mV. Although superoxidized water is intended to be generated fresh at the point of use, when tested under clean conditions the disinfectant was effective within 5 minutes when 48 hours old 537. Unfortunately, the equipment required to produce the product can be expensive because parameters such as pH, current, and redox potential must be closely monitored. "

What is my takeaway? The potential is there, but as with many new or newish technologies, "the devil is in the details." Would I rely on it? Not personally; I would stick to a weekly or biweekly soak and scrub with good old bleach.

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