Hi, @taco. Welcome to Mayo Connect.
I am a liver and kidney transplant recipient, and over the 15 years with my transplant, my medications have been adjusted. My transplant team is the one who makes the changes based on my routine labs which are now drawn every 3 months. On a couple of occasiona, I have contacted my nurse coordinator to describe some uncomfortable symptoms, and upon extra lab test, my tacrolimus levels were higher than my assigned target range. That is when they had me lower my level, and redo labs in 2 weeks to be certain that the level suitable to protect my organs. My liver team and my kidney team work together to establish my best dosage and/or medications.
I have taken cellcept and tacrolimus since day 1. I was taking prednisone for several years, until research showed that I did not need to take it anymore. At that time I was tapered off of it. Different medicines work differently and so each one of us might react differently.
Each of us is going to be prescribed the dosage according to our individual needs. That is why we are so carefully monitored throughout oue lives.

@taco, How long ago was your kidney transplant? Are you having side effects that are bothering you? What has your transplant team had to say or suggest regarding those side effects?