Vitamin B12 deficiency and small fiber neuropathy

I also had deficient in vitamin B 12 and have Neuropathy. I have numbness all over by body there is no feeling anywhere and is been 1 1/2 years ago and the numbness is still there. I took vitamin B12 under the tung how do you spell tongue, tongue, my tongue until it came up to normal. It didn’t work I was to far gone.
I’m sorry I hope it comes back for you.

Hi @shordae, I'm sorry you're experiencing nerve issues . It's understandable that you're scared from feeling odd symptoms through your body. I remember feeling the very same way when I started having nerve sensations
- numbness, electric shocks, tingles, skin burning. Fear is a natural response to something that you've never felt before and it's normal to have concern if you feel you are in harm. It's the good old fight or flight mode.

I was diagnosed with small fiber neuropathy from a B12 deficiency so the first thing I did was begin B12 shots weekly and after a few months I was able to go to a oral supplement. Neuropathy can in some cases be slowed down or reversed by supplementing B12 but a neurologist would be the best to explain to you how long something like that would take or if it was reversible. I take nerve medication now and I'm doing better. Have you seen a neurologist yet?

Hi Rachel
What nerve medication are you using please?

How are you doing now? Any updates?

@mikeg0822 and @moylandavis - yes, I neglected to mention the MTHFR gene. Thanks for bringing it up. I am homozygous for the a1298c mutation. Just started a different injectable form of b12 and am going to see if that is more helpful.
Have you had your copper level checked?

I have been experiencing neuropathy-like symptoms for almost 6 months, although my EMG and physical exams show no significant nerve damage. After numerous tests they determined my B-12 was 315 (low). It has increased to over 800 with supplements. My neurologist said it can take 6-12 months for symptoms to improve. I have been following the B-12 Society (based in the UK) on Facebook. They are insistent that if you have neurological symptoms you need B-12 injections to get the vitamin into your cells. They feel that with oral supplements Vitamin B-12 only sits in the bloodstream and doesn't truly heal the body. My neurologist disagrees and actually told me to go off B-12 since my numbers have dramatically increased (I still take B complex and a multi-vitamin). I am so confused and feel there are no clear answers when it comes to B-12 deficiency. Magnesium glycinate has been a godsend for me to get restful sleep at night. Best wishes to you for a full recovery.

B12 and neuropathy & bloodwork
Hello. Looking for answers. Any advice would be appreciated. Events: July 26 2023 out of no where I began to get full body tingling, pin & needles, burning sensation with sporadic itch. My skin felt I was sunburned. Sleeping my back felt as if I was lying on sandpaper. Not real severe, but scary. July 27 my ankles were aching & my front of my calves. July 28 went to ER. At this time I was on antibiotic Cefpodoxime proxetil for UTI. Hospital ran labs. They said all looked good. No explanation why my skin was feeling this. It's now been over a month. Symptoms progressed. Went back to ER onn August 24, there ran many labs. The said I have PN and prescribed Gabapentin. I reviewed my labs on My Chart with a fine tooth comb. These are my concerns: My MCHC is above normal range at 37. The normal range is 32-36. My trends are as follows starting from August 24 to June 3: 37, 36, 37, 36, 36. I researched high MCHC (UWH) and it says: High MCH scores are commonly a sign of macrocytic anemia. This condition occurs when the blood cells are too big, which can be a result of not having enough vitamin B12 or folic acid in the body. Although they did a B12 test is was "Borderline", mine was 268. The normal range is 213-816. I am 55 digits to be considered B12 deficient. I have only 2 trends, August 24 at 268 and Sept. 13 2021 at 330. With the information I provided,could I be experiencing neuropathy symptoms from B12 deficiency.