Vitamin B12 deficiency and small fiber neuropathy

Posted by mikeg0822 @mikeg0822, Sep 23, 2022

Hi everybody,
I was hoping to possibly connect or receive advice. Has anybody been diagnosed with small fiber neuropathy caused by a vitamin B12 deficiency? I'm 28 years old and have always been healthy otherwise. I've never smoked, always maintained my fitness level, and have always had a relatively healthy diet. My B12 deficiency went unnoticed for 13 months, and I finally began getting treated for it about eight months ago. Doctors are hopeful I can recover but aren't sure. Does anybody have any experience with this? Any advice would be welcome. Thank you!

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@michellemu1992

I also had deficient in vitamin B 12 and have Neuropathy. I have numbness all over by body there is no feeling anywhere and is been 1 1/2 years ago and the numbness is still there. I took vitamin B12 under the tung how do you spell tongue, tongue, my tongue until it came up to normal. It didn’t work I was to far gone.
I’m sorry I hope it comes back for you.

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How are you now? Did you ever try b12 injections? What were your numbers?

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I have body-wide neuropathy, and my B12 has been elevated for the last ten years (1,450 - 2,500) without supplementation. I haven't yet found a doctor to test me to see if the B12 is merely circulating in my bloodstream and not being absorbed at the cellular level. I have read that elevated levels of vitamins in the blood can mean they are not being assimilated.

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@sallylynn

Thank you for responding. I had a B12 test August 24. My B12 is 268. Normal range: 213 - 816 pg/mL. Mine is very low in the normal range. I am almost 63 years old, so I am post menopausal. I have next to none estrogen left in my body. However, I refuse to take estrogen in any shape or form. Actually I had a pelvic exam in July, and the doctor could "Visibly" see the thinning of my "V" walls.
I would like to share this with you as to possibly why I got"Out of nowhere" neuropathy symptoms:
***I was using MICONAZLE NITRATE
at the same time my skin sensations occurred.

DRUG CLASS: Miconazole is in a class of antifungal medications called IMIDAZOLES.

IMIDAZOLE side effects: The most common side affect is nausea/vomiting/loss of appetite/headache/hair loss and "PARESTHESIA".

PARESTHESIA symptoms: Burning/prickling sensation felt in hands, arms, legs,feet but can occur in other parts of body. The sensations, which happen WITHOUT WARNING & is usually painless describes as tingling, numbness,skin crawling, itching. In most cases the paresthesia is transient resolving on it's own in a few days, or weeks.In some cases the "Condition" as being persistent, lasting more than 6 months.A small amount of cases, it is permanent.
* This I know as fact,the symptoms described above are 100% exactly what I experienced to the T. I have never experienced in my life paresthesia until July 26, and it was without warning.
**My neuropathy is getting less. Once in awhile now I will get a brief "Itchs" randomly on my body. Just so you know, I told the ER & my Doctor I was actively using Miconazole Nitrate for my yeast infection. I did the research. On July 28, in detail I told ER my symptoms. I told them I was using Miconazole Nitrate suppositories. I told ER on August 24 the day the "Neuropathy" happened, I was using Miconazole Nitrate. No one put it together. Can I say this was the culprit? I am leaning on yes more than no. What are your thoughts? Oh, I am surprised the Hospital didn't advise me to start B12 since my B12 is very low, they said my B12 was fine. I am a measly 56 digits from actually being "Deficient".

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How are you doing? I realize this your post is from some time ago, I had almost the same thing happen to me. I was using an antifungal prescription med for my skin when my symptoms began. I was then diagnosed with B12 deficiency and began treatment. I still struggle with causation questions.

Have you seen any progress? I kept reporting the antifungal when my symptoms first hit and no one thought it was relevant. I’m better in some ways, but not in one of my symptoms.

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Hi. Twice in my life I have had neuropathy symptoms (numbness arms) clincially apparent associated with low B 12. Both times were associated with protein pump inhibitor (PIP) usage for stomach issues. Both times my symptoms resolved with oral B12 supplementationl. I continue on oral B12 and try to minimize PIP usage. B12 levels are normal. I am now older and have subtle balance and lower leg proprioception issues (manageable). I walk slowly, turn slowly, do lots of walking and use a walking stick. I do wonder if any of my lower leg issues reflect the earlier B12 deficiencies, but there is no way of really knowing. Good luck to you.

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@michaelsz

Hi. Twice in my life I have had neuropathy symptoms (numbness arms) clincially apparent associated with low B 12. Both times were associated with protein pump inhibitor (PIP) usage for stomach issues. Both times my symptoms resolved with oral B12 supplementationl. I continue on oral B12 and try to minimize PIP usage. B12 levels are normal. I am now older and have subtle balance and lower leg proprioception issues (manageable). I walk slowly, turn slowly, do lots of walking and use a walking stick. I do wonder if any of my lower leg issues reflect the earlier B12 deficiencies, but there is no way of really knowing. Good luck to you.

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I appreciate your response. I had not used any protein pump inhibitors when my symptoms started. The B12 has helped my foot paraesthesia, but not my bitter taste problem. That coincided with the antifungal. So glad you are doing well!

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@michaelsz

Hi. Twice in my life I have had neuropathy symptoms (numbness arms) clincially apparent associated with low B 12. Both times were associated with protein pump inhibitor (PIP) usage for stomach issues. Both times my symptoms resolved with oral B12 supplementationl. I continue on oral B12 and try to minimize PIP usage. B12 levels are normal. I am now older and have subtle balance and lower leg proprioception issues (manageable). I walk slowly, turn slowly, do lots of walking and use a walking stick. I do wonder if any of my lower leg issues reflect the earlier B12 deficiencies, but there is no way of really knowing. Good luck to you.

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For my trigeminal neuralgia, 10 METHYLCOBALAMIN pills daily stopped pain next day. Absorbed under tongue. You are on the right track with B12. Supports REMYELINATION of our nerves.
Good luck, James 82 NZ

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I was diagnosed with peripheral neuropathy a year and a half ago. After a couple months, my doctor started B12 shots. My fatigue lessened but the neuropathy continues. I doubt it will get better for me. I hope you do well.

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@kathieb48

I was diagnosed with peripheral neuropathy a year and a half ago. After a couple months, my doctor started B12 shots. My fatigue lessened but the neuropathy continues. I doubt it will get better for me. I hope you do well.

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When I talked to my neurologist about the paresthesia in my feet and how it has greatly reduced, but not disappeared, he said it could take a year or longer. I’m not giving up.

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Mike, Am surprised someone as young as you
has B12 deficiency.
B12 medicinal name is COBALAMIN. Coba is short for cobalt, a mineral found in soil. Grazing animals pull soil with grass and so consume B12. Meat eaters therefore get B12 by eating plenty of meat. Many people eat little meat . They tend to be low B12.
Suggest you try METHYLCOBALAMIN. That is a readily
absorbed under tongue B12.. I take 10 daily.
B12 remyelinates nerves. Go for it now that u understand. James 82 NZ

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