Vitamin B12 deficiency and small fiber neuropathy

Hi, @mikeg0822 - I've had autonomic neuropathy symptoms since early 2007, officially diagnosed in 2016 (yes, it took that long). I was also diagnosed with low vitamin B around the same time in 2016 (yes, the docs missed this one too). I've also had low copper, diagnosed in 2013, which can cause neuropathy. I have so many GI issues that I don't absorb enough vitamin B, so I've been on injections for a few years. The levels are still low. I'm currently being treated and monitored - still on injections and oral supplementation, but not certain if they're being absorbed and cells are utilizing them - this is the big question. I have a good diet and am athletic. (Was a competitive runner up until this wretched disease took over.) I'm hoping that once my levels of both B and copper are back to normal and sustained that my symptoms resolve. This would be a dream come true. But, it might have been too long to be able to turn everything around. With you being young and catching this soon, you might have better results.

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I have been experiencing neuropathy-like symptoms for almost 6 months, although my EMG and physical exams show no significant nerve damage. After numerous tests they determined my B-12 was 315 (low). It has increased to over 800 with supplements. My neurologist said it can take 6-12 months for symptoms to improve. I have been following the B-12 Society (based in the UK) on Facebook. They are insistent that if you have neurological symptoms you need B-12 injections to get the vitamin into your cells. They feel that with oral supplements Vitamin B-12 only sits in the bloodstream and doesn't truly heal the body. My neurologist disagrees and actually told me to go off B-12 since my numbers have dramatically increased (I still take B complex and a multi-vitamin). I am so confused and feel there are no clear answers when it comes to B-12 deficiency. Magnesium glycinate has been a godsend for me to get restful sleep at night. Best wishes to you for a full recovery.

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Very! Ever time I try and research something I find that symptoms that are the usual don’t match mine. My mom and sis have the same symptoms except mom has burning and sis does not. Mine just feels like buzzing and sometimes it feels like a pulsating sensation.

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B12 and neuropathy & bloodwork
Hello. Looking for answers. Any advice would be appreciated. Events: July 26 2023 out of no where I began to get full body tingling, pin & needles, burning sensation with sporadic itch. My skin felt I was sunburned. Sleeping my back felt as if I was lying on sandpaper. Not real severe, but scary. July 27 my ankles were aching & my front of my calves. July 28 went to ER. At this time I was on antibiotic Cefpodoxime proxetil for UTI. Hospital ran labs. They said all looked good. No explanation why my skin was feeling this. It's now been over a month. Symptoms progressed. Went back to ER onn August 24, there ran many labs. The said I have PN and prescribed Gabapentin. I reviewed my labs on My Chart with a fine tooth comb. These are my concerns: My MCHC is above normal range at 37. The normal range is 32-36. My trends are as follows starting from August 24 to June 3: 37, 36, 37, 36, 36. I researched high MCHC (UWH) and it says: High MCH scores are commonly a sign of macrocytic anemia. This condition occurs when the blood cells are too big, which can be a result of not having enough vitamin B12 or folic acid in the body. Although they did a B12 test is was "Borderline", mine was 268. The normal range is 213-816. I am 55 digits to be considered B12 deficient. I have only 2 trends, August 24 at 268 and Sept. 13 2021 at 330. With the information I provided,could I be experiencing neuropathy symptoms from B12 deficiency.

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B12 and neuropathy & bloodwork
Hello. Looking for answers. Any advice would be appreciated. Events: July 26 2023 out of no where I began to get full body tingling, pin & needles, burning sensation with sporadic itch. My skin felt I was sunburned. Sleeping my back felt as if I was lying on sandpaper. Not real severe, but scary. July 27 my ankles were aching & my front of my calves. July 28 went to ER. At this time I was on antibiotic Cefpodoxime proxetil for UTI. Hospital ran labs. They said all looked good. No explanation why my skin was feeling this. It's now been over a month. Symptoms progressed. Went back to ER onn August 24, there ran many labs. The said I have PN and prescribed Gabapentin. I reviewed my labs on My Chart with a fine tooth comb. These are my concerns: My MCHC is above normal range at 37. The normal range is 32-36. My trends are as follows starting from August 24 to June 3: 37, 36, 37, 36, 36. I researched high MCHC (UWH) and it says: High MCH scores are commonly a sign of macrocytic anemia. This condition occurs when the blood cells are too big, which can be a result of not having enough vitamin B12 or folic acid in the body. Although they did a B12 test is was "Borderline", mine was 268. The normal range is 213-816. I am 55 digits to be considered B12 deficient. I have only 2 trends, August 24 at 268 and Sept. 13 2021 at 330. With the information I provided,could I be experiencing neuropathy symptoms from B12 deficiency.

Jump to this post

B12 and neuropathy & bloodwork
Hello. Looking for answers. Any advice would be appreciated. Events: July 26 2023 out of no where I began to get full body tingling, pin & needles, burning sensation with sporadic itch. My skin felt I was sunburned. Sleeping my back felt as if I was lying on sandpaper. Not real severe, but scary. July 27 my ankles were aching & my front of my calves. July 28 went to ER. At this time I was on antibiotic Cefpodoxime proxetil for UTI. Hospital ran labs. They said all looked good. No explanation why my skin was feeling this. It's now been over a month. Symptoms progressed. Went back to ER onn August 24, there ran many labs. The said I have PN and prescribed Gabapentin. I reviewed my labs on My Chart with a fine tooth comb. These are my concerns: My MCHC is above normal range at 37. The normal range is 32-36. My trends are as follows starting from August 24 to June 3: 37, 36, 37, 36, 36. I researched high MCHC (UWH) and it says: High MCH scores are commonly a sign of macrocytic anemia. This condition occurs when the blood cells are too big, which can be a result of not having enough vitamin B12 or folic acid in the body. Although they did a B12 test is was "Borderline", mine was 268. The normal range is 213-816. I am 55 digits to be considered B12 deficient. I have only 2 trends, August 24 at 268 and Sept. 13 2021 at 330. With the information I provided,could I be experiencing neuropathy symptoms from B12 deficiency.

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I have concerns myself about B12. As a teen, I used to get weekly B12 shots that counteracted my extreme tiredness. Now docs refuse to give shots and I take a 1000 mcg B12 pill each day. I’m still exhausted everyday. Doctors should listen to us more because we’re in the body with the problems!

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I have concerns myself about B12. As a teen, I used to get weekly B12 shots that counteracted my extreme tiredness. Now docs refuse to give shots and I take a 1000 mcg B12 pill each day. I’m still exhausted everyday. Doctors should listen to us more because we’re in the body with the problems!

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