PSA detectable 18 mos after prostatectomy

Hello Group:

I had Robotic Prostate Surgery Aug. 2, 2022. Had 5 PSA tests since surgery. Here are the levels 0.06; 0.11; 0.12; 0.13; 0.13. Met with Radiation Oncologist last week after last PSA test and he recommended that I have another PSA test in April. He said he follows the American Guidlines that which indicates radiation from 0.18 to 0.23. Has anyone experienced rising PSA post surgery and if so, what were the next steps?

I recommend considering these inputs. They help to explain potential next steps, when, and why. At your level of PSA, the challenge is knowing where to radiate.
"What to ask when PSA is rising after the initial treatment:"
PCF - https://www.pcf.org/about-prostate-cancer/diagnosis-staging-prostate-cancer/psa-rising/what-to-ask-when-your-psa-is-rising-after-initial-treatment/
"Rising PSA after initial treatment. PCRI" - https://www.youtube.com/watch?v=X_FtOBTIOj0

Hello Group:

I had Robotic Prostate Surgery Aug. 2, 2022. Had 5 PSA tests since surgery. Here are the levels 0.06; 0.11; 0.12; 0.13; 0.13. Met with Radiation Oncologist last week after last PSA test and he recommended that I have another PSA test in April. He said he follows the American Guidlines that which indicates radiation from 0.18 to 0.23. Has anyone experienced rising PSA post surgery and if so, what were the next steps?

has any one used xtandi drug for cancer

Hello Group:

I had Robotic Prostate Surgery Aug. 2, 2022. Had 5 PSA tests since surgery. Here are the levels 0.06; 0.11; 0.12; 0.13; 0.13. Met with Radiation Oncologist last week after last PSA test and he recommended that I have another PSA test in April. He said he follows the American Guidlines that which indicates radiation from 0.18 to 0.23. Has anyone experienced rising PSA post surgery and if so, what were the next steps?

Well, I think I'll be looking at next steps soon. I had non-nerve sparing RARP on 6/24/24 with pathology of stage pT3a, Gleason 9, 60% Intraductal Carcinoma, and Cribriform Patterned 4. Today, my first 3 month PSA was 0.26 mg/ml. My Mayo team says it isn't BCR until I have two results over 0.2; however, I was also told that a test false reading was highly unlikely and it is very unusual to have a reading this high this quickly - they expressed concern. My incontinence is improved since surgery,
but the team said that salvage radiation will stop any improvement and may worsen it. I'm scheduled for a follow-up PSA in 6 weeks. I know what the treatment protocol is but I also know that my situation isn't optimal. I read all the studies saying that even with high risk PC, 10-15 years was highly likely but I am also reading that early BCR with doubling rates < 6 months puts 5 year survival at < 20%. I have my fingers crossed that my next reading does not reflect accelerated PSADT. I'm a bit anxious now!

So sorry to hear this news and your anxiety is totally understandable - it’s OK to be fearful in light of your numbers.
BUT, so many advances have been made in even just the last few years! You will probably be put on some form of ADT right now to stop the cancer in its tracks and then you can exhale while your team works on the next steps.
As has been posted on other threads, radiation initiated immediately or down the line has the same outcomes so don’t sweat it out waiting for it to begin. You may be on ADT for many months - perhaps even different forms - before your team is ready to do radiation.
So many others on this board have faced similar scary situations and have come out on the other side with fantastic results and a hopeful future. YOU WILL TOO!

So sorry to hear this news and your anxiety is totally understandable - it’s OK to be fearful in light of your numbers.
BUT, so many advances have been made in even just the last few years! You will probably be put on some form of ADT right now to stop the cancer in its tracks and then you can exhale while your team works on the next steps.
As has been posted on other threads, radiation initiated immediately or down the line has the same outcomes so don’t sweat it out waiting for it to begin. You may be on ADT for many months - perhaps even different forms - before your team is ready to do radiation.
So many others on this board have faced similar scary situations and have come out on the other side with fantastic results and a hopeful future. YOU WILL TOO!

I had RP in 2008 with no follow up treatments. Eleven years later my PSA results were rising every 3 months. It was recommended that I see a oncologist and after MRIs cancer was detected in the prostate bed. I began hormone treatment for 6 months while having 36 proton radiation treatments. My PSA scores initially were undetectable but that was short lived. They're now approaching a 4 at 3.84. Three PET scans have not been able to show any cancer yet. I don't particularly want to begin treatment unless a PET scan can show me where and what to treat.
Just don't be too hasty to begin treatment. Involve your urologist and a oncologist to listen and learn. Do plenty of research.