Kevzara

Posted by healthy56 @healthy56, Sep 14 11:21am

I am curious about other’s experience with KEVZARA. I am currently taking 11 mg of Prednisone, down from 60 mg in April 2024. I am continuing to experience pain and stiffness daily, especially in the late evening and the morning. I am also fatigued most days. I am on an anti-inflammatory diet, walk daily and do a little restorative yoga. My Rheumatologist suggests going back up to 12.5 mg but I do not think that will be helpful as it will only lengthen the time I am on a drug that appears to not be helpful. She has suggested KEVZARA and we are now waiting on approval from my insurance company. My questions are: should I wait a bit and stay at 11 mg to see if anything changes (I have been on this dose for 4 weeks) before I start KEVZARA? Is it too soon in my treatment to start a biologic? It seems as tho my autoimmune system is not responding to the Prednisone or maybe I need more patience? My doctor was vague on these questions. Thank you in advance, I really appreciate this forum!

Interested in more discussions like this? Go to the Polymyalgia Rheumatica (PMR) Support Group.

Hola yo llevaba tomando prednisona desde hace 5 años pero me ha dado osteosporosis catarata y gastritis hace 4 meses deje de tomarla porque mi reumatologo me mando kevzara llevo 12 inyecciones de kevzara y tuve que empezar de nuevo con 2.5 mg de prednisona no soportaba el dolor me ha aliviado muy poco me da mucho dolor en los brazos y hombros y se me ponen rigidos y debil sin poderlo mover yo tenia la esperanza de aliviarme con la kevzara pero no me ha hecho nada es horrible estos dolores me gusta leer estos comentarios. Gracias

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@evita

Hola yo llevaba tomando prednisona desde hace 5 años pero me ha dado osteosporosis catarata y gastritis hace 4 meses deje de tomarla porque mi reumatologo me mando kevzara llevo 12 inyecciones de kevzara y tuve que empezar de nuevo con 2.5 mg de prednisona no soportaba el dolor me ha aliviado muy poco me da mucho dolor en los brazos y hombros y se me ponen rigidos y debil sin poderlo mover yo tenia la esperanza de aliviarme con la kevzara pero no me ha hecho nada es horrible estos dolores me gusta leer estos comentarios. Gracias

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I would think you might need more than 2.5 mg of prednisone before starting Kevzara. It takes a few months for the effects of Kevzara to start working. You still need to taper off Prednisone slowly because your cortisol level is probably very low after 5 years on Prednisone.

I was started on a different biologic than Kevzara. It eventually worked but it still took me more than a year to get off Prednisone completely. I was still taking 10 mg of prednisone as my "lowest effective dose" before starting the biologic.

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@dadcue

I would think you might need more than 2.5 mg of prednisone before starting Kevzara. It takes a few months for the effects of Kevzara to start working. You still need to taper off Prednisone slowly because your cortisol level is probably very low after 5 years on Prednisone.

I was started on a different biologic than Kevzara. It eventually worked but it still took me more than a year to get off Prednisone completely. I was still taking 10 mg of prednisone as my "lowest effective dose" before starting the biologic.

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Hola DadCue gracias por contestarme me ha dado un poco de animo cuando me dice que un biologico demoro unos meses en hacerle efecto ojala a mi me funcione para ver si mi vida cambia con estos dolores sufro mucho. Gracias y que dios la bediga

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@evita

Hola DadCue gracias por contestarme me ha dado un poco de animo cuando me dice que un biologico demoro unos meses en hacerle efecto ojala a mi me funcione para ver si mi vida cambia con estos dolores sufro mucho. Gracias y que dios la bediga

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Don't forget that it can also take a year for your cortisol level to improve after you can stay on a low enough dose of Prednisone. My endocrinologist said 3 mg of Prednisone for "an extended period of time" should be low enough to give my adrenals a chance to recover. My endocrinologist said for "as long as it takes" but I might need to take a small amount of Prednisone for the rest of my life.

I was on Prednisone for 12 years and still got off Prednisone so never lose hope!

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@dadcue

Don't forget that it can also take a year for your cortisol level to improve after you can stay on a low enough dose of Prednisone. My endocrinologist said 3 mg of Prednisone for "an extended period of time" should be low enough to give my adrenals a chance to recover. My endocrinologist said for "as long as it takes" but I might need to take a small amount of Prednisone for the rest of my life.

I was on Prednisone for 12 years and still got off Prednisone so never lose hope!

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Gracias Gracias oiré sus buenos consejos y que a usted le vaya bien

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@evita

Gracias Gracias oiré sus buenos consejos y que a usted le vaya bien

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I'm not giving medical advice. I'm just sharing what my experience was.

Good luck! I wish you well with your endeavor to taper off prednisone.

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@jlo2252

@wilmingtonemperor
At one point I was put on Meloxicam (“mobic”) for a bad flare of my inflammatory arthritis. I took it with prednisone and a gastric protector, Carafate(I’m very sensitive to NSAIDS).
This combination worked very well with no bad effects on a short term basis.

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Hello healthy56!
I wouldn’t hesitate start KEVZARA. It has been a life changer for me. Early in 2022 I developed PMR and was on prednisone for 2-1/2 years. It took forever to wean myself off (cyling up and down dosage) when my rheumatologist suggested this biologic. I had no reservations as I was so desperate. And amazingly, it started working within 2 to 3 weeks. I have been off prednisone nine months and managing my PMR and RA with Kevzara. They will need to run complete blood panels and test you for tuberculosis before prescribing. Fortunately, my blood labs have continued to be absolutely perfect during this time, whereas on prednisone and many other drugs for RA, I had liver and numerous other deficits. In January 2024, while investigating prescription drug coverage, I found Aetna to be the best, requiring only $3200 out of pocket and the rest was written off. As you likely know, it’s a very expensive drug, but well worth it. I just turned 70 years old and I’m feeling like my 60-year-old self once again, FYI, I am an active, fit male Developed PMR early in 22, in June of that year I caught Covid (Vaccinated) then had long Covid for another year, eventually developing rheumatoid arthritis. I highly recommend KEZARA, and hopeful that it will continue working. Best of luck on your journey.

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Hello -it has been a while since I posted but I have done well on Kevzara. The only hiccup now is that the funds only last about 6 months (15,000) so now I am trying to go every 4 weeks for my injection. My BCBS picks up $2400 but then I would need to pay out of pocket $1600 monthly. I may check into the Aetna. I can tell I’m not as good now as when I was taking every 2 weeks. What a bummer these meds are so costly.

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I thought kevzara was supplemented by manufacture ?

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