@gigiv I hear all the time about CoQ10 - along with many other supplements, and tend to let it "go in one ear and out the other." But just this week, I began taking 3 new meds for my heart & cholesterol, and the nurse mentioned that the cardiologist recommends it with these.
Since I also have Bronchiectasis and Asthma, I decided to take a look and see what Mayo says... https://www.mayoclinic.org/drugs-supplements-coenzyme-q10/art-20362602
Hmm, sounds like a good idea with those new meds, but what about my lungs? Well, with a deep dive into Google Scholar, I can see where the research is headed: https://journals.sagepub.com/doi/full/10.1177/17534666231208628
So a few things seem to say CoQ10 is good for asthmatic lungs because it has antioxidative and anti-inflammatory properties, especially for people on long-term inhaled corticosteroids. But, there have been no specific measurable studies reported yet.
And a couple of studies say the "ubiquinol" (CoQ2) version is more bio-available than ubiquinone (CoQ10). So another deep dive led to this review of hundreds of studies reported in scientific literature over 20 years: https://link.springer.com/article/10.1007/s11886-023-01992-6#ref-CR18
Their conclusions? "...In contrast to CoQ10, no CoQH2 study could clearly demonstrate a reduced cardiovascular mortality; (III) the used concentrations are much higher in studies investigating CoQH2.
According to these results, we conclude that based on the medical data available, CoQ10 is the more promising supplement to prevent cardiovascular diseases and to treat patients with heart failure. Further arguments for CoQ10 are the additive effect in combination with selenium [30, 31••] and the reduction of adverse effects of statin therapy by supplementation with CoQ10 [44,45,46]. Additionally, in all clinical trials included in this study, patients proceeded with their previous medication (statins, antihypertensives and others) and no interactions between CoQ10 and medicines could be observed..."
So, after all of this, what do I plan to do? Follow my cardiologist's advice and add a CoQ10+selenium supplement to my diet. I'll probably try 100mg first since I am a small person. And I'll take it with a meal containing some fat or a snack of nuts since it needs fat to be absorbed.
I spoke to a local cardiologist, a woman, who is taking CoQ10 at 200 mg every other day. That sealed the recommendation for me. So, 100 mg per day is apparently good. Even 200 mg daily. I have read where it restores the reduction in systemic CoQ10 that statin medication reduces, so that sounds good. I've read where CoQ10 also reduces arterial plaque or at least stabilizes the formation rate, Pantothenic acid (B-5) is apparently good for reducing arterial plaque as well, but I've not read any clinical studies that confirms it. My PCP also said he has read no info on B-5 being of benefit. Have you ever gotten a broad CT scan of your chest and torso, from lungs to abdomen to see how your arterial plaque situation looks? I have a little plaque around my aortic valve, my carotid arteries and abdominal arteries, but not worrisome. I'm 77 years old and not a doctor.
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I spoke to a local cardiologist, a woman, who is taking CoQ10 at 200 mg every other day. That sealed the recommendation for me. So, 100 mg per day is apparently good. Even 200 mg daily. I have read where it restores the reduction in systemic CoQ10 that statin medication reduces, so that sounds good. I've read where CoQ10 also reduces arterial plaque or at least stabilizes the formation rate, Pantothenic acid (B-5) is apparently good for reducing arterial plaque as well, but I've not read any clinical studies that confirms it. My PCP also said he has read no info on B-5 being of benefit. Have you ever gotten a broad CT scan of your chest and torso, from lungs to abdomen to see how your arterial plaque situation looks? I have a little plaque around my aortic valve, my carotid arteries and abdominal arteries, but not worrisome. I'm 77 years old and not a doctor.
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