Hello, were you diagnosed with PV? Some people can just do phlebotomies or just do the hydroxyurea from what I’ve read. If your platelets are high you need both usually. I was diagnosed almost two years ago with PV getting phlebotomies about every eight weeks and take the hydroxyurea 3X a week. Took about 5 months to get the dosage correct but I’m aware that could be changed accordingly. Just wondering if I will always need the phlebotomies. Honestly, I prefer that to the drugs but he said as long as my platelets remain over 600, safe number for me, I need the meds. Currently dwindle around 500.