Cavity close-up in 12 months
I read an article published in Nature Magazine on Sep 10, 2024. Cavity can close up, taking 12 months on average ! It is such a promising article for cavitary disease patients!
https://www.nature.com/articles/s41598-024-71971-6
Interested in more discussions like this? Go to the MAC & Bronchiectasis Support Group.
Early detection and treatment of mac/ntm's is important. Old dying infections can create scar tissue in and around the cavity
That would be awesome if it were the case for the majority of patients. This is why treating sooner than later at any stage is so important. The "study" they talk about isn't anything different than what has been the typical treatment. I think it also depends on how large the cavity is when starting treatment. I formed a 10 cm cavity within 30 days. I was put on all the oral med mentioned and had no improvement in the size of the cavity but did have improvement in my symptoms. Once I added the inhaled Arikayce to all the other meds, the cavity shrunk to 4 cm. That was 4 years ago. The cavity isn't getting larger or smaller but the walls are a bit thinner. Treatment definitely helps to keep stability. The article makes the "cavities can close within a year" sound promising but......
I hope it worked on most people as well. We are all surgery reluctant. Also hate the side effects of medication. Yes only about 40% , not 100%. There are also other factors like size, age,medicine....I doubt they have arikayce at that time range 2009-2020. But shrinking of size means better healing rate and lower mortality. 🙂 😀
I wouldn't even count on 40%
Age hasn't seem to have been much of a factor either.
On many of the other support pages, there's such a wide variety of ages that haven't had any closure/complete collapse of the cavities. It's difficult to go by only 1 study
Totally agree. With rapid technology and advances medicine development, there may be a new antibiotics to treat cavity soon. Surgery has higher risk esp lung resection. If your life quality is great, just hold on there!
I also read another article in Nature magazine that a new antibiotics works so well on gram negative bacteria but does not do harm to immune system has been invented!!
Maybe race? It is conducted in Korea.
Their diet is so healthy .
Someone also says that they have new cavity after old one closed up.
Yes it seems complicated. I wish there is a new medicine to conquer MAC! It seems to be a super bug!!!
What was the new one called?
@suzyqueen Here is the link: 🙂 Its name is lolamicin.
https://www.nature.com/articles/s41586-024-07502-0
P.s. I pasted the wrong link this morning, 🙂
https://www.news-medical.net/news/20240529/New-antibiotic-lolamicin-shows-promise-in-fighting-drug-resistant-infections.aspx#:~:text=To%20tackle%20the%20many%20problems,by%20the%20pharmaceutical%20company%20AstraZeneca.
If you read all the way to the bottom of the link that Helen provided, you will see thsat it cites many more studies as well. I looked at a couple of them, and cavity shrinkage does seem to point to decreased risk.
Also, as she mentioned, we have a new tool in hand now - Arikayce was only in trial in 2019 when my MAC was being treated - one I could not qualify for. I would have tried it in a minute because I did not convert under the Big3