@bkouv If you have never used it before, be aware that fluorouracil can produce very reactive spots. That has been my experience. When used as a preventative, I didn't really think there were any areas I had to be careful of. But lo and behold! About 7-10 days later the medication was showing there were small areas to address.

I think the fact that your nose has so much in the way of mucous membrane present might be why there are precautions. I have used it very sparingly on my nose for that reason. Does this make sense to you?
Ginger