Ivermectin for Prostate Cancer? (Being studied)

Posted by tvz @tvz, Apr 7 4:56pm

I am 54 and have Gleason 3+4 in 8% of one lobe. My PSA rose from 8.1 to 9.6 in the past 6 months. I’ve heard Ivermectin has potential to slow growth of cancer cells. Has anyone tried IVM or any other medication that has been shown to slow growth?

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

@hammer101

tvz & dannos - I was a few years older (55) than you guys when I was diagnosed with Gleason 7 (4+3). It was definitely a shocker, I am very active, healthy, and had just retired from my corporate job to reduce stress and enjoy life. I am a big advocate of consistent motion - Even though my wife and I retired fairly early, we both stay busy with our hobby jobs. Long story short, I immediately did a significant amount of research to understand what treatment options would give me the best chance to meet my person goals moving forward. Obviously, treatment options and personal goals overlap - Everyone has their own unique life goals and a single treatment plan does not meet all circumstances. For me, my goals were (#1 - #10) 30+ years of cancer free life to spend with my wife, son, friends/family; (#11) continence - High want but definitely not a necessity; (distant #12) sexual function - Definitely nice to have, but nowhere close to life and continence.

Based on my research, a robotically assisted radical prostatectomy was the only option that met all of my personal goals and provided for a backup plan if the cancer decided to come back. At that point, I researched to find the best possible hospital for the surgery and the best doctor at that hospital. I decided that distance and convenience were not going to prevent me from getting the best possible care for my prostate cancer. I went with Mayo-Rochester and Doctor Igor Frank. What an amazing hospital, staff, and doctor. I am now 2 1/2 years out from my robotically assisted radical prostatectomy (removed prostate, seminal vesicles, 9 lymph nodes). For myself, I had full continence after 6-9 months, full erectile function after 12-18 months, and PSA continues to be undetectable (prostate cancer contained to prostate, negative margins). You never know if the cancer will come back, but for me, I am confident I will be in the 80% probability group of not having BCR. My confidence is based on the doctor, hospital and staff expertise. I would highly highly recommend doing your homework and finding the best possible hospital and doctor to provide your treatment. Your quality of life, for the rest of your life, will depend on the competence of those performing the treatment.

Based on my research and discussions after my treatment, I personally would recommend a radical prostatectomy for someone that is healthy/active and is relatively young (everyone has a different definition for young). However, as I said earlier, the treatment decision is very personal and one treatment plan does not meet every man's situation and goals.

Best of luck and pray all goes well for both of you.

Jim

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Great post. Logical and informed. It sounds like you have your priorities in order as well. Best of luck to you. Prayers as well.

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@dcgreenzone

Dr. Dennis Hancock (iirc) is testing Liposomal Ivermectin for solid tumors (Injectable) his org is called Mountain Valley MD fyi.

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Didn't know it could be injectible, nor liposomal. Interesting.

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@hammer101

tvz & dannos - I was a few years older (55) than you guys when I was diagnosed with Gleason 7 (4+3). It was definitely a shocker, I am very active, healthy, and had just retired from my corporate job to reduce stress and enjoy life. I am a big advocate of consistent motion - Even though my wife and I retired fairly early, we both stay busy with our hobby jobs. Long story short, I immediately did a significant amount of research to understand what treatment options would give me the best chance to meet my person goals moving forward. Obviously, treatment options and personal goals overlap - Everyone has their own unique life goals and a single treatment plan does not meet all circumstances. For me, my goals were (#1 - #10) 30+ years of cancer free life to spend with my wife, son, friends/family; (#11) continence - High want but definitely not a necessity; (distant #12) sexual function - Definitely nice to have, but nowhere close to life and continence.

Based on my research, a robotically assisted radical prostatectomy was the only option that met all of my personal goals and provided for a backup plan if the cancer decided to come back. At that point, I researched to find the best possible hospital for the surgery and the best doctor at that hospital. I decided that distance and convenience were not going to prevent me from getting the best possible care for my prostate cancer. I went with Mayo-Rochester and Doctor Igor Frank. What an amazing hospital, staff, and doctor. I am now 2 1/2 years out from my robotically assisted radical prostatectomy (removed prostate, seminal vesicles, 9 lymph nodes). For myself, I had full continence after 6-9 months, full erectile function after 12-18 months, and PSA continues to be undetectable (prostate cancer contained to prostate, negative margins). You never know if the cancer will come back, but for me, I am confident I will be in the 80% probability group of not having BCR. My confidence is based on the doctor, hospital and staff expertise. I would highly highly recommend doing your homework and finding the best possible hospital and doctor to provide your treatment. Your quality of life, for the rest of your life, will depend on the competence of those performing the treatment.

Based on my research and discussions after my treatment, I personally would recommend a radical prostatectomy for someone that is healthy/active and is relatively young (everyone has a different definition for young). However, as I said earlier, the treatment decision is very personal and one treatment plan does not meet every man's situation and goals.

Best of luck and pray all goes well for both of you.

Jim

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Jim, thanks for sharing. Did Dr. Frank make any attempt to spare nerves? Congrats on your excellent recovery!

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@dannos

I'm taking curcumin 95 and CBD oil. I'm on day two of 1 fenben 222 and 1 curcumin 95, with food, in the morning and the same at night, CBD throughout the day.

I had my numbers tested just before I started

I'm gonna try it for 6 days a week for a month then test the numbers and see where I'm at.
I'm open to your suggestions, what do you think?

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I took Meriva - a pharmaceutical dose of Curcumin and Turmeric for two years before diagnosis. A COMPLETE failure.

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@heavyphil

I took Meriva - a pharmaceutical dose of Curcumin and Turmeric for two years before diagnosis. A COMPLETE failure.

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Meriva is not an anti parasitic medication…
Fenbendazole is, look into it and good luck

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@dannos

Meriva is not an anti parasitic medication…
Fenbendazole is, look into it and good luck

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Yes I was responding to the Curcumin query. The anti parasitic has been widely discussed here. Whatever - ‘zole’ you want to choose and there are many, no one knows IF it works or how much you need to kill the cancer and not the host. Anecdotal tales don’t count when your life is at stake.

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Reminder:
Ivermectin is used to treat certain parasitic roundworm infections. Here is further information about its use in humans https://www.mayoclinic.org/drugs-supplements/ivermectin-oral-route/proper-use/drg-20064397. Ivermectin is also used in veterinary care as an anti-parasitic. It is NOT safe for humans to take ivermectin used in veterinary medicine.

Please talk to your doctor before taking any repurposed (off-label) drugs, over-the-counter medications or supplements that claim to fight or cure cancer. Ask your pharmacist about any drugs purchased online. These drugs and supplements are not regulated and may included ingredients or dosages not identified on the label.

Why the hype about ivermectin? Because there is hope.
Researchers are studying ivermectin to see if it may be used as an anti-cancer drug and early studies show promise. This research is in the early stages (laboratory and mice studies) and has not yet been tested in human trials.

Ivermectin is not a proven standard treatment for prostate cancer.

Ivermectin combined with other chemotherapy drugs or targeted drugs is being studied in early clinical (human) trials and shows promise in patients for whom conventional chemotherapy has not worked in some cancer types. It may be effective against drug-resistant cancer cells.

As with all information shared by members on Mayo Clinic Connect, such as messages, images, advice, URLs, and any other material, it is for informational purposes only and is not a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your health. Never disregard professional medical advice or delay in seeking it because of something you have read on the community. https://connect.mayoclinic.org/blog/about-connect/tab/community-guidelines/

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I don’t knock or blame anyone for trying Ivermectin or FenBen when all else has failed. Might try it myself if I HAVE to at an end stage point in my treatment (a long way off I hope).
But one thing to remember is that lowering PSA is not necessarily killing the cancer or even slowing it down. Saw Palmetto also lowers PSA but doesn’t treat or cure PCa. PSA is just one byproduct of glandular or tumor function. Who knows if lowering this particular number is what we should really be focused on?
I just saw that a company came out with a PSE score - it combines PSA with 5 other markers usually present in prostate cancer. It is something like 94% predictive for cancer as opposed to PSA which is far from it.
Anyone on Ivermectin or other off label drugs should look into this test and have it done a few times to see if levels of these other markers are also dropping. If so, you are definitely making progress!

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@heavyphil

I took Meriva - a pharmaceutical dose of Curcumin and Turmeric for two years before diagnosis. A COMPLETE failure.

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Meriva is not a FenBen type drug . This is like an apple and orange . Turmeric is a anti inflammatory with some good uses ... But FenBen totally different . Some interesting studies .

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@heavyphil

I don’t knock or blame anyone for trying Ivermectin or FenBen when all else has failed. Might try it myself if I HAVE to at an end stage point in my treatment (a long way off I hope).
But one thing to remember is that lowering PSA is not necessarily killing the cancer or even slowing it down. Saw Palmetto also lowers PSA but doesn’t treat or cure PCa. PSA is just one byproduct of glandular or tumor function. Who knows if lowering this particular number is what we should really be focused on?
I just saw that a company came out with a PSE score - it combines PSA with 5 other markers usually present in prostate cancer. It is something like 94% predictive for cancer as opposed to PSA which is far from it.
Anyone on Ivermectin or other off label drugs should look into this test and have it done a few times to see if levels of these other markers are also dropping. If so, you are definitely making progress!

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You make some really good points . PSA is a predictor of a bunch of things , like a enlarged prostate and so on . FenBen is not a spooky drug . Ivermectine and its relatives have been on the market for humans for years and years - trying it I cant would hurt you and it should not be considered to be a 'end stage ' option . With you Dr's approval , try it and see if you PSA does come down and other markers look better . Many people have reported very many positives . Plus if you have travelled much a good dose of Ivermectine may be useful . When was your last decal matter analyses for parasites of All types - probably never ? Dr's never think of it . I asked the Dr for one after returning from Indonesia . Positive for a couple parasites - zero symptoms ! Indonesia is some kind of political S$it hole . I have been there so many times and it gets worse by the month ( danger wise ) . They are swimming in oil too but the regular people never get their hands on any of the money ...unlike Brunei . Being a pilot I have travelled the world many times , and studied culture and societies ( one of my hobbies ) . I live now PT on Luzon about 6 months a year and work from Cebu airport and MNL and Clarke .

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