Natural high levels of B12 and B6

After research i had the doctor check me for DNA problem which I have so i have to take L-Methylfolate with B12 L-methyfolate is the metabolically processed folate that is needed for the body to process B12 Active form.

I had the same problem about a year ago. I started having peripheral neuropathy by my neurologist shortly after getting badly dehydrated. My neurologist did just about every test possible and the only thing that showed up was high vitamin B6 and I was only taking about 25 mg. She told me to stop all B6 immediately. It took a few weeks but I started to get better. About 3 months later I was pretty much back to normal. Apparently many of us (especially those with European ancestry) has a MTHFR gene mutation that causes our body to absorb vitamin B6 (and some other supposedly water soluble vitamins as well) instead of just urinating out the excess. I would suggest stopping not only vitamin B6 supplements but also all fortified foods like cereal and protein powders because many of them contain B6 as well.

I find B12 injections four times a year extremely beneficial. What is strange is how quickly it works. I'm sure doctors would say it can't make a difference in 20 mins, but they're wrong. If I could have one everyday I would.

It's interesting you said that my mothers maiden name was Johnson and European decent LOL I do know I have a gene where I don't have the enzyme needed to process and absorb B12 wonder if it effects B6 as well.

Studies show taking vitamin B12 is beneficial, studies show it can be harmful. I guess it all comes down to risk versus reward, it works for me, maybe not for others. I did a Google search and found a study done by the Mayo Clinic indicating vitamin B12 isn't harmful. It wouldn't surprise me if there are similar studies showing the complete opposite.

We may be related!! I have not had that particular test but my son has and he (and I am almost positive me too) have the MTHFR gene mutation which makes our bodies absorb some B vitamins like B6 instead of urinating them out like most water soluble vitamins. I am okay taking B12 and it doesn't bother me but I absolutely cannot take B6 in any supplement. I thought for sure that I had Parkinson's or MS and my neurologist did as well before she found that my B6 was too high. If you know that you have that or a similar gene mutation, I would stay away from all B vitamins until you get a blood test to check your levels. Have a blessed day!

What was the blood level of B6 that is or was considered high? If you wouldn’t mind sharing that.
I have a high b12 but not absorbing so take some special b12 supplement.

Thanks

At the particular lab I used the max limit was 24 and mine was 36. I know that doesn't sound too bad but it made my feet entirely numb and gave me internal tremors all over plus heart palpitations. It took a few months getting off B6 to get back to normal but that definitely was causing my problems. I don't absorb B12 well unless I take the methylcobalamin B12 that dissolves in my mouth. Everyone is different but my B12 levels are excellent using that.

Thanks so much. I’m stopping all supplements with B6. Mine was 66 at a lab that max was 50.
Did you avoid foods containing B6 or just supplements?
Thanks.

Tonyde: Could you tell me specifically what kind of injections you were given? There are many B vitamins.
Thanks!