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Natural high levels of B12 and B6

Posted by patriciaschulz1950 @patriciaschulz1950, Sep 5, 2023

I have PN - and continue to determine the cause. Current blood work show elevated levels of B12 and B6 (I take no supplements or vitamins or drink energy drinks, etc). My neurologist is not concerned and suggested that I start taking B12 1000mcg daily - I know that your body disposes B12, but she could not answer or seemed concerned that both were elevated. I have read the value of B12 for nerve damage, but am hesitant to start this vitamin. Comments please.

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tonyde | @tonyde | Feb 15 10:15am

I have taken vitamin B tablets; my vitamin B levels reached low normal. My primary care doctor suggested trying B injections for leg pain. It was a game changer for me. I highly recommend trying it.

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1 reply
jobli0 | @jobli0 | Feb 15 8:25pm
In reply to @ray666 "Hello again, @chme I, too, have found doctors to be a little wanting when it comes..." + (show)
@ray666

Hello again, @chme

I, too, have found doctors to be a little wanting when it comes to nutritional matters. Even the clinicians in my neurologist's office seem somewhat vague when it comes to replying to questions about B6. The links @johnbisjop has sent make for good reading. EB-N5 has a website; unfortunately, all you'll find is glossy marketing material. However, I do trust the product's underlying substance.

Cheers!
Ray

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C

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jrn57 | @jrn57 | Feb 16 12:38pm

My understanding is that vitamin B12 maximum limit for adult male is 100 mg. I was taking sublingual B12 at much higher dosages before I learned that too much B12 can aggravate PN

Vitamin B six, be very careful with it. My PCP indicates too high of a level of B6 can be detrimental to cardiovascular

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ann707 | @ann707 | Feb 17 10:12am

Since, it turns out, 2015 my level of B12 have been twice the normal. This year, yes I was slow to figure this out, I checked what I could possibly be doing to have these high levels. I drink soy milk three time a day for the calcium. Turns out it is supplemented with B12. So mystery solved. I still have peripheral neuropathy so it doesn't seem to help that.

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1 reply
chme | @chme | Feb 17 10:25am
In reply to @ann707 "Since, it turns out, 2015 my level of B12 have been twice the normal. This year,..." + (show)
@ann707

Since, it turns out, 2015 my level of B12 have been twice the normal. This year, yes I was slow to figure this out, I checked what I could possibly be doing to have these high levels. I drink soy milk three time a day for the calcium. Turns out it is supplemented with B12. So mystery solved. I still have peripheral neuropathy so it doesn't seem to help that.

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Thank you for commenting. Do you mind sharing what the blood level of b12 you had?

I have a high level of blood b12 but dr thinks I have a moderate problem with absorption.

Everything is so complicated.

Can we really do anything to cure neuropathy or just keep from getting worse? That’s the question nobody knows about.

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1 reply
mdamiani57 | @mdamiani57 | Aug 22 8:05pm
In reply to @patriciaschulz1950 "Was your neurologist concerned? Mine are high too without ever taking supplements or vitamins. My neurologist..." + (show)
@patriciaschulz1950

Was your neurologist concerned? Mine are high too without ever taking supplements or vitamins. My neurologist just brushed it off.

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Mine too said it was probably diabetes but I'm not even considered to be diabetic only Pre-diabetic but anyway non of my doctors seem to have an answer for the B6 being so high they said stop taking B6 I said I don't take any they looked perplexed and shook their head I have a feeling it's drug induced.

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mdamiani57 | @mdamiani57 | Aug 23 9:04am
In reply to @patriciaschulz1950 "Thank you so much for your quick response. I look forward to reading the information on..." + (show)
@patriciaschulz1950

Thank you so much for your quick response. I look forward to reading the information on the above links. My B levels have been high for about a year. First the B12 was very low, so they put me on 1000 MCG of B12 - which I took for about 6 months. When I had blood tested it was 2800 , so doctor told me to cut back to every other day, but also suggested that we take blood test again after flushing system of B12. So I went without for four weeks, tested and this time both levels of B12 (1200) and B6 (38.8). This was the first time testing for B6... I don't know the right questions to ask the neurologist as she was not concerned with B6. All reports that I have read is that B12 is good for neuropathy - but since I am still at 1200, I should stay off the supplement for now.

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High B6 can mimic the effects of low B12 high B6 can also cause neuropathy

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mdamiani57 | @mdamiani57 | Aug 23 9:10am
In reply to @chme "Thank you for commenting. Do you mind sharing what the blood level of b12 you had?..." + (show)
@chme

Thank you for commenting. Do you mind sharing what the blood level of b12 you had?

I have a high level of blood b12 but dr thinks I have a moderate problem with absorption.

Everything is so complicated.

Can we really do anything to cure neuropathy or just keep from getting worse? That’s the question nobody knows about.

Jump to this post

After research i had the doctor check me for DNA problem which I have so i have to take L-Methylfolate with B12 L-methyfolate is the metabolically processed folate that is needed for the body to process B12 Active form.

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johnsonje62 | @johnsonje62 | Aug 24 2:46pm
In reply to @mdamiani57 "Mine too said it was probably diabetes but I'm not even considered to be diabetic only..." + (show)
@mdamiani57

Mine too said it was probably diabetes but I'm not even considered to be diabetic only Pre-diabetic but anyway non of my doctors seem to have an answer for the B6 being so high they said stop taking B6 I said I don't take any they looked perplexed and shook their head I have a feeling it's drug induced.

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I had the same problem about a year ago. I started having peripheral neuropathy by my neurologist shortly after getting badly dehydrated. My neurologist did just about every test possible and the only thing that showed up was high vitamin B6 and I was only taking about 25 mg. She told me to stop all B6 immediately. It took a few weeks but I started to get better. About 3 months later I was pretty much back to normal. Apparently many of us (especially those with European ancestry) has a MTHFR gene mutation that causes our body to absorb vitamin B6 (and some other supposedly water soluble vitamins as well) instead of just urinating out the excess. I would suggest stopping not only vitamin B6 supplements but also all fortified foods like cereal and protein powders because many of them contain B6 as well.

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1 reply
nemo183 | @nemo183 | Aug 24 3:20pm

I find B12 injections four times a year extremely beneficial. What is strange is how quickly it works. I'm sure doctors would say it can't make a difference in 20 mins, but they're wrong. If I could have one everyday I would.

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