Azilect for PD

Asking for your experience with rasagiline (azilect) (dose per day) in combination with carvidopa-levadopa.

I took rasagilne-standard dose but felt no different so stopped taking and only take C/L. Took for at least 6 mo.

I took it for about 2 weeks and had some bad side effects. It was 9 years ago, but it is on my med list as allergic to med listing. A few meds for different issues I end up in the 1-2% of people that have rare side effects.

My husband was diagnosed with PD 7 years ago. He’s been doing pretty well through medication and intense exercise 🤞🏻

Recently he wasn’t feeling so well. Saw his Movement Dr. as it turned out, he was having bad side effects of Rasagline. (He’s been taking it for at least 5 years). His gait was off. When he walked his left hand would curl behind his back. Acting out violently in his dreams. More muscle stiffness, etc. he’s been off of Resagline for 4 days now and he says, he hasn’t felt so good for such a long time. It’s not a cure, but a warning that, sometimes certain drugs could turn against you.

It's also a good idea to review you med with your doctor from time to time. I take 21 meds - PD, asthma, high bp, high choresterol, low thyroid,, particularly if you are fetting meds frim mire than 1 doctor. I try to do it once a year. Things change: the may have discovered an new interaction between meds. Mabe it's ok to take med A with med B, and ok to take med B wirh Med C, BUT you shouldn't take all 3 of them. Or mabe some newbproblem with a particular med had come yonlight; maybeva new med has been released tgart wiuld be better for you. I include mybscedulr fir taking my meds, because maybe i've been taking somethun on a full stomach and i snhould have been taking ut on an empty somach OR, maybe you've been taking a med for 10 years for osteopoenia and it turns out that if you takr it oire tha 7 years, it can makeyour bones brittle. ( really happened to ne!)

He sees his PD Dr. every six months. He’s keeps on top of things. He does see different doctors for different issues. He’s fortunate to have wonderful care.

He is, indeed fortunate, as am I. And I believe that we can help our
overworked health care professionals by watching things like this and
taking on some responsibilities, because they are human just like us, and
sometimes may not be able to track some things as closely as they would
wish. There are so many new drugs, and side effects that may come to light
after we are prescribed a med, that even the most rigorous trials may not
have found, because they aren't going to have 7-year trials and have to
wait for real-world use to figure out that beyond 7 years, you shouldn't
take it any more. There is so much coming out that iyou doctor could easily
miss the notice. Even so, imagine what would have to be done to review
patient files for meds taken and how long they've been taking them.
Electronic records can help some, but even they require time and attention.