Success with low dose naltrexone for Autoimmune disorders

Posted by julie868 @julie868, Feb 13, 2020

Low Dose Naltrexone, otherwise known as LDN, seems to be helping a lot of people lately who have all different types of autoimmune disorders.
The information I read sounds very interesting and would like to know if anyone has tried it personally?

The theory that I read says that many autoimmune issues are caused by a deficiency in endorphins, endorphins regulate the immune system. LDN temporarily blocks the body's natural endorphin production for a few hours, this tricks the body into thinking it needs to increase endorphin production. When the blockade wears off, all the endorphins are released into the body, regulating the immune system and providing natural pain relief for the rest of the day. Apparently, LDN can increase your endorphins by up to 300%

LDNscience.org has a lot of information and research about it. You can also look at the writer, Annie Habler (@hablerannie) on Medium.com who wrote an article recently about the fascinating background and history of LDN.

Please let me know if you have tried it and what your experience was like. If you could let me know any details your condition,the dosage you used, any side effects, etc it would be helpful.

Thank you!

Interested in more discussions like this? Go to the Autoimmune Diseases Support Group.

suetex | @suetex | Jul 31, 2024

In reply to @rosemaryconte "I tried a few times in fits and starts….hung in but each time RX renewal came..." + (show)

I guess I was luckey in that it help one type of pain I had the first night. The ulcers in my small intestine took a couple of months. I guess that's the up side of having multiple autoimmune diseases. You have a lot to work with. I take 2 mg and it seems right to me. I tried 4 mg and notice no difference. Gave it a month then gave it up.

klittr3637 | @klittr3637 | Oct 28, 2024

In reply to @aus12 "Interested in the results of using low dose naltrexone in autoimmune patients" + (show)

Me too

5416jh | @5416jh | 3 days ago

I have Hashimotos thyroiditis and I've recently been diagnosed with Myasthenia Gravis. I'm looking into LDN as an alternative medication to steroids and immunosuppressants that are normally prescribed for MG

clj9821 | @clj9821 | 2 days ago

It has been suggested for me and I’m interested in hearing from others that have used it. Thank you!

suetex | @suetex | 2 days ago

I am totally convinced that it put my Crohn's in remission. I am now medication and symptom free. However, Crohn's is at the top of the list for resposiveness to LDN so I wouldn't assume that it would work for every one. But side effects (if any) are minimal and seem reversable so read up on it, find yourself a doc and start low. It might be just what you need.

vostie | @vostie | 1 day ago

I am using LDN for Long COVID. It does seem to cut the pain from the chronic inflammation by about 50%...and that allows me to sleep better. I usually do not remember my dreams but I do on LDN. The dreams are vivid but not nightmares. I sometimes feel quite tired after taking the LDN dose but it is gone in an hour or two. No other side effects at 4.5 mg per day.

You do need to start low and work up to the max dose of 4.5 mg per day.

kkathysan | @kkathysan | 1 day ago

@julie868 I have been taking LDN 4 mg. Dosage for about 2 years. My Dr. prescribed it to help with my Chronic Active Epstein Barre’ Virus. I have had this illness for 40 years and I can say it took a while, but I could see a difference in how I felt after a few months. I take it at night when I go to bed and I do notice a slight headache in the first 30 minutes of taking it. After that I am asleep and I see no other side affects. I will keep taking it if it is helping my immune system. I need all the help I can get. I hope it helps you too!

God Bless!
Kathy

suetex | @suetex | 1 day ago

In reply to @kkathysan "@julie868 I have been taking LDN 4 mg. Dosage for about 2 years. My Dr. prescribed..." + (show)

It is nice to hear of these good results from such different circumstances. I don't have any side effects from it and I am on 2 mg, (4 mg didn't make any difference so why bother?!) Now that my Crohn's is in remission, I don't get a relapse if I have to go off the LDN. I've been off it as long as a month with no backlash.