How long does it take the medication mirtazapine to work?

Posted by roadqueenie @roadqueenie, Apr 18, 2020

I’m being switched from Viibryd to Mirtazipine (slowly) over two weeks. Mirtazipine started at 15mg and I’m now at 30mg and I take Buspar 10mg for depression and anxiety. I also take Ativan 1mg three times a day. My questions are: how long has it taken these drugs to build up and help symptoms and can the anxiety and depression make me feel physically sick? I just don’t feel well, don’t fell like doing anything except laying on the couch or recliner, I have no motivation to even go for a car ride with my husband and it’s scaring me. I’ve had a complete blood work up and I’m healthy! But I’m nauseous most of the time and food doesn’t appeal to me so I’m living on bananas, rice, ham and other bland food. Anyone else been through this please and thank you?

Interested in more discussions like this? Go to the Depression & Anxiety Support Group.

@gerryvigus56

I finally got in to see my doctor and he's titering me back to Paxil, what's nice is it's a very short time before I go back to my Pacil, less than a week, can't wait to feel good again

Jump to this post

I am so glad you saw your doctor and will be going back on Paxil. Please keep in touch! God Bless

REPLY
@gerryvigus56

I know I will always be on antidepressants, some people have to go on them because of a situation being trauma whatever, with me I just started having panic attacks, horrible anxiety etc , my mother was manic depressive and my father had depression and on my father's side he had 2 brothers with depression who had to hold into sanitoriums for it, of course this was decades ago and that's what happened, I have been told that it can definitely be in families and I truly believe that's why I have it

Jump to this post

Depression also runs in my family. I too believe that I will always be on some kind of antidepressant. I have come to believe that its fine, as long as I am feeling better and enjoying life again. I wish you luck - keep me posted.

REPLY
@myacct123

How long does it take the medication mirtazapine to work? When is a good time to come off the medication? It’s been a couple of months. No improvement. Why is the doctor trying it again? I am concerned about brain fog. Anyone else experience that with this drug?

Jump to this post

I had been taking Wellbutrin for 10-15 years when I felt like I was sliding back toward the dark hole of suicidal depression from which I spent 8 years climbing out. My psychiatrist prescribed Mirtazapine 45mg as an add on, and it's been a good maintenance combination. I never noticed any negative side effects and haven't ever tried stopping it. I don't want to mess with what's working to treat my major depression.

Because of my history of suicidal ideation my doctors are attentive to my mental well-being, which I surely appreciate. Managing medications for multiple medical conditions requires an ongoing need to be especially aware of interactions between my meds. Sometimes I have to weigh the benefits with the risks, and watch out for any problems. I've certainly had an education! There are times when being obsessive about being informed pays off.

I'm wondering what side effects others have experienced. I don't take Mirtazapine for sleep - I use a BiPap because of sleep apnea.

Jim

REPLY
@jimhd

I had been taking Wellbutrin for 10-15 years when I felt like I was sliding back toward the dark hole of suicidal depression from which I spent 8 years climbing out. My psychiatrist prescribed Mirtazapine 45mg as an add on, and it's been a good maintenance combination. I never noticed any negative side effects and haven't ever tried stopping it. I don't want to mess with what's working to treat my major depression.

Because of my history of suicidal ideation my doctors are attentive to my mental well-being, which I surely appreciate. Managing medications for multiple medical conditions requires an ongoing need to be especially aware of interactions between my meds. Sometimes I have to weigh the benefits with the risks, and watch out for any problems. I've certainly had an education! There are times when being obsessive about being informed pays off.

I'm wondering what side effects others have experienced. I don't take Mirtazapine for sleep - I use a BiPap because of sleep apnea.

Jim

Jump to this post

I agree with you 100%. You have to weigh the benefits with the risks! I am about to increase the Mirtazapine to 15 mg, but I am taking it hoping for increased appetite. So far so good on the 7.5mg. I am continuing with Cymbalta and going off Lexapro and Atenolol because of low blood pressure because I lost so much weight. I feel some side effects from this but hoping they will stop when I increase the Mirtazapine and stop the other two.

Keep us posted!
God Bless

REPLY
@mayomee

Yes, I'm a senior heart patient. Started with 7.5 Mirtazapine, doctor suggested 15 mg. It didn't help. Side effects hurt.Went back to 7.5.Seems to help with anxiety and sleep . And did get better over time. Been on the 7.5 for about 3-4 months. Average on depression. No side effects on the 7.5 dosage.

Jump to this post

Did you go back down to 7.5mg without any tapering from 15mg
John

REPLY
@bigjohnscho

Did you go back down to 7.5mg without any tapering from 15mg
John

Jump to this post

Went straight to the lower dose. Been about 60 plus days. 7.5 works better for me. 67 year old male. Plan on staying on it . Take it at bedtime with 5 mg Melatonin. On very low dose .5 Alprazolam as well.

REPLY
@tricia7

You sound just like me. I’ve been trying to get back to some kind of normal for 4 years. I got sick with Lyme disease in 2020 and it set off something awful. Changed my life. Unleashed viruses such as EBV and HPV. My labs usually show I’m fighting an infection. I’ve lost over 40lbs after losing my appetite and nausea. I feel you about this being upsetting. My PCP insists this is because I’m depressed. I’ve since started seeing a counselor and take antidepressants but nothing is working. I’m even doing TMS treatments. Still no appetite and exhausted. I feel like I live a hell.
I’m sorry you are going through this. I wish something could help us. My PCP diagnosed Fibromyalgia and Chronic Fatigue. I just turned 61 and feel like my life is over. I don’t like taking these meds but don’t know what else to do. I just had a CT Scan with contrast that only showed a cyst on my liver so it appears this is not GI related.
I wish you the best as well. God Bless.

Jump to this post

I have been ill for many, many years. My PC doctor believes I have two different kinds of autoimmune but can never get a specialist to concur. My symptoms have worsened over the years. Recently I started losing function of both my hands (worse in the right). I was scared and reached out to my PC doctor. He put me on a 1-week dose of prednisone which made me feel significantly better. Unfortunately, after the prednisone wore off the loss of function in my hands came back. I always feel better all over when on prednisone, but you cannot stay on it long term. My PC ran extensive blood work up and told me that my levels on the EBV were "very" high from a past infection. I was infected over 27 years ago, so I was very confused. He told me my body just needed time to heal. I would think after 27 years my body would be healed. I started doing a lot of research and Britian has made a lot of progress with EBV studies as has Hopkins in the US. Unfortunately, most doctors in the US still do not recognize or even attempt to manage EBV or acknowledge the links between autoimmune, certain cancers, chronic joint pain, etc. Even after everything I read and reading bundles of comments from people with levels as high as mine, I still don't understand what is going on. However, the studies done by Hopkins directly linked EBV to certain types of cancer, autoimmune diseases, severe chronic joint pain and thinning of the bones. It puts you at a lot higher risk. My doctor is currently doing some additional testing for myeloma cancer on me. He still has no idea what is wrong with my hands, and I sent him the article about the findings because I have chronic joint pain, and have a lot of symptoms of autoimmune disease, along with a lot of other symptoms that go hand-in-hand with autoimmune. My PC is not interested in looking at the studies from Hopkins on EBV. Sad. I pray we all get answers.

REPLY
@chrissy67

I have been ill for many, many years. My PC doctor believes I have two different kinds of autoimmune but can never get a specialist to concur. My symptoms have worsened over the years. Recently I started losing function of both my hands (worse in the right). I was scared and reached out to my PC doctor. He put me on a 1-week dose of prednisone which made me feel significantly better. Unfortunately, after the prednisone wore off the loss of function in my hands came back. I always feel better all over when on prednisone, but you cannot stay on it long term. My PC ran extensive blood work up and told me that my levels on the EBV were "very" high from a past infection. I was infected over 27 years ago, so I was very confused. He told me my body just needed time to heal. I would think after 27 years my body would be healed. I started doing a lot of research and Britian has made a lot of progress with EBV studies as has Hopkins in the US. Unfortunately, most doctors in the US still do not recognize or even attempt to manage EBV or acknowledge the links between autoimmune, certain cancers, chronic joint pain, etc. Even after everything I read and reading bundles of comments from people with levels as high as mine, I still don't understand what is going on. However, the studies done by Hopkins directly linked EBV to certain types of cancer, autoimmune diseases, severe chronic joint pain and thinning of the bones. It puts you at a lot higher risk. My doctor is currently doing some additional testing for myeloma cancer on me. He still has no idea what is wrong with my hands, and I sent him the article about the findings because I have chronic joint pain, and have a lot of symptoms of autoimmune disease, along with a lot of other symptoms that go hand-in-hand with autoimmune. My PC is not interested in looking at the studies from Hopkins on EBV. Sad. I pray we all get answers.

Jump to this post

My doctor won’t acknowledge EBV is doing something to me. My titers are off the chart and indicate past and current infection. When I question this the answer I get is I just run high.

It’s been over 40 years since I had mono so I don’t understand how I can have a current infection. I’m not offered any treatment. I just live chronically fatigued and worry that this is going to be the rest of my life now. It’s an awful way to live. I’m trying to figure out how to cope with this. It’s scary and depressing. I feel like my life is over.

REPLY
Please sign in or register to post a reply.