1. < Brain & Nervous System

Vitamin B complexes.

Posted by bigjohnscho @bigjohnscho, Jun 25 9:45am

I take a vit B complex capsule everyday for my PN. Lately I learned that some of the vitamins are not in their most bioavailable form, for example B1 thiamine should be Benfotiamine and B12 must be methylcobalim. Has any one sussed this problem out.

Interested in more discussions like this? Go to the Brain & Nervous System Support Group.

bigjohnscho | @bigjohnscho | Jul 1 1:49am
In reply to @johnbishop "I take 1200 mg daily (600 mg morning and evening). One of the side effects some..." + (show)
@johnbishop

I take 1200 mg daily (600 mg morning and evening). One of the side effects some people have with higher dosages is nausea so it might help to start with a lower amount if you have nausea when you try it. Here's some information on the topic:

"How much alpha-lipoic acid should you take?
Because alpha-lipoic acid is an unproven treatment, there is no established dose. However, studies have used between 600-1,800 milligrams daily for diabetes and neuropathy; one review concluded that the evidence is convincing for the use of 600 milligrams daily for three weeks on symptoms of diabetic neuropathy. Some studies have used intravenous alpha-lipoic acid instead of oral supplements."
-- Alpha-Lipoic Acid Supplements: https://www.webmd.com/diabetes/supplement-guide-alpha-lipoic-acid

Jump to this post

Can you take alpha lipoic acid long term.

REPLY
bigjohnscho | @bigjohnscho | Jul 1 3:29am
In reply to @johnbishop "I take 1200 mg daily (600 mg morning and evening). One of the side effects some..." + (show)
@johnbishop

I take 1200 mg daily (600 mg morning and evening). One of the side effects some people have with higher dosages is nausea so it might help to start with a lower amount if you have nausea when you try it. Here's some information on the topic:

"How much alpha-lipoic acid should you take?
Because alpha-lipoic acid is an unproven treatment, there is no established dose. However, studies have used between 600-1,800 milligrams daily for diabetes and neuropathy; one review concluded that the evidence is convincing for the use of 600 milligrams daily for three weeks on symptoms of diabetic neuropathy. Some studies have used intravenous alpha-lipoic acid instead of oral supplements."
-- Alpha-Lipoic Acid Supplements: https://www.webmd.com/diabetes/supplement-guide-alpha-lipoic-acid

Jump to this post

I have just started ALA .I am starting on 200mg but I am not sure when to take it. I take other meds at 8am and 6pm, 8pm can you advise me please
John

REPLY
2 replies
Mentor
John, Volunteer Mentor | @johnbishop | Jul 1 6:38am
In reply to @bigjohnscho "I have just started ALA .I am starting on 200mg but I am not sure when..." + (show)
@bigjohnscho

I have just started ALA .I am starting on 200mg but I am not sure when to take it. I take other meds at 8am and 6pm, 8pm can you advise me please
John

Jump to this post

I’ve been taking R-ALA since 2016. I take it in the morning along with my blood pressure medication and in the evening. It’s important to discuss any supplements you take with your doctor. I talked with my doctor when I first started back in 2016 to make sure there were no issues.

REPLY
Mentor
John, Volunteer Mentor | @johnbishop | Jul 1 6:41am
In reply to @bigjohnscho "I have just started ALA .I am starting on 200mg but I am not sure when..." + (show)
@bigjohnscho

I have just started ALA .I am starting on 200mg but I am not sure when to take it. I take other meds at 8am and 6pm, 8pm can you advise me please
John

Jump to this post

I’m an early riser and take my meds and morning supplements around 6 to 7 am and evening ones around 5 pm.

REPLY
bigjohnscho | @bigjohnscho | Jul 5 5:19am

I have searched the various treatments for peripheral neuropathy until I’m blue in the face and I am no nearer selecting one. The only one that seems to show promise is R-ALA and Benfotiamine. Unfortunately when I tried them I got an upset stomach so I’ve stopped taking them. The clinical trials I’ve seen seem to show that R-ALA and Benfotiamine are the only supplements that work. I’m completely baffled. I took a relatively low dose I.e. 200mg R-ALA and 300mg Benfotiamine. Any advice please. John

REPLY
2 replies
Mentor
John, Volunteer Mentor | @johnbishop | Jul 5 6:59am
In reply to @bigjohnscho "I have searched the various treatments for peripheral neuropathy until I’m blue in the face and..." + (show)
@bigjohnscho

I have searched the various treatments for peripheral neuropathy until I’m blue in the face and I am no nearer selecting one. The only one that seems to show promise is R-ALA and Benfotiamine. Unfortunately when I tried them I got an upset stomach so I’ve stopped taking them. The clinical trials I’ve seen seem to show that R-ALA and Benfotiamine are the only supplements that work. I’m completely baffled. I took a relatively low dose I.e. 200mg R-ALA and 300mg Benfotiamine. Any advice please. John

Jump to this post

If you are taking the supplements on an empty stomach that might make it more likely to cause nausea. Might be worth trying to take a bite of a banana or other food when you take the supplements to see if it helps with the nausea.

REPLY
steven120566 | @steven120566 | Jul 6 6:58am

I take 300mg of Benfotiamine with dinner, as it is fat soluable. I believe it is helping keep arteries healthier, as I have found ALA has no noticable effect. But I should probably take R ALA too.

REPLY
bigjohnscho | @bigjohnscho | Jul 6 7:47am

Does ALA work for none diabetic peripheral neuropathy

REPLY
bigjohnscho | @bigjohnscho | Jul 6 7:51am

Does anyone have ALA injected

REPLY
denisejones00 | @denisejones00 | Jul 6 9:05am

Has anyone heard of the MTHFR gene? I was tested and have this gene. Basically this means that my body does not metabolize B Vitamins well. B vitamins are critical for nerve and brain health. I use methylized B Vitamins and it has really been a game changer for my numbness and tingling in my legs. The MTHFR test is offered several companies. Seeking Health and Life Extension are two companies that I know offer this test. Millions of people carry this gene.

REPLY
1 reply
View MoreView Less
Please sign in or register to post a reply.