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Nivolumab aka Opdivo
I'm stage 2a nscl cancer, had wedge resection and I'm scheduled for chemo. I read that nivolumab( OPDIVO) has had some very good success with early stage lung cancer. Does anyone have personal experience with this?
Especially in Canada or in conjecture with KRAS G12D?
THANKS IN ADVANCE
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Nivolumab was the first immunotherapy used in lung cancer. There have been many more since.
If you are to have chemo, they will likely go with standard of care which is carboplatin and bevacizumab (Avastin) with the immunotherapy drug keytruda.
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2 Reactions@zora0121, there are several discussions in the Lung Cancer support group related to Opdivo (nivolumab). You may find these helpful:
- Anyone on Opdivo (nivolumab) for metastic lung cancer?
https://connect.mayoclinic.org/discussion/opdiva/
- Did you have a serious reaction to Opdivo (nivolumab)?
https://connect.mayoclinic.org/discussion/reactions-to-opdivo/
- Has anyone had the Opdivo (nivolumab) / Yervoy (ipilimumab) protocol?
https://connect.mayoclinic.org/discussion/opdivo-yervoy-combination/
What treatment will you be receiving?
At this point I'm just scheduled for chemo with
Pemetrexed and cisplatin.
I am wondering about receiving immunotherapy in addition to chemo, given my Kras G12D status. It appears I should've been given this perioperatively. Studies give much better result if given pre resection. I'm wondering if there is any data post operative given my stage 2a status?
Seems like everything is for stage 3 or 4 if postoperative???