Yes - How did you fare ... appears from your comments ypu are fighting a type of 'resistant' Hyper-Tension ... does anyone (of course, including yourself) use LISINOPRIL with TENORMIN ... side-effects vs. stability? Continue with exploring safe avenues ..

Was your last message above meant for me, @jacko? My hypertension is for sure resistant, but probably not in a classically defined way. I've been treated for it for 20 years and have used a wide range of popular medications, including Lisinopril and Tenormin (Atenolol), recently at the same time. My Lisinopril dose (once a day, maximum 40mg) is taken before going to bed. My nephrologist says it has helped both my hypertension and my chronic kidney disease.

Tenormin is a beta blocker that was not for me because it would slow down my already low normal pulse rate of 50 bpm. However, A-fib changed that two years ago, lightening compressions of my heart muscles and speeding my pulse rate up to between 80 and 90 bpm (not hazardously high, I know). That left room in my pulse rate for a beta blocker, and I'm now on Carvedilol (Coreg) 25mg twice a day.

Those two medications are just fine for me, although we're still fooling around with dosages, raising them to get better control of my BP. I also take Amiloride, a potassium-sparing diuretic (10 mg twice a day). Together, the three keep my BP under control, although a little high -- high enough so new nurses look askance whenever they take my BP.

Side effects have not caused me any anxiety or particular discomfort, although my taste and smell are not as acute as before and I have short bouts with sexual dysfunction. Is any of this applicable to your concerns?

Hello,<br><br>Is 175mg of Lopressor daily and still have uncontrolled blood pressure. I was told by my endocrinologist that thyroid medication is the culprit. Anyone else have this problem? I have Hashimoto's and take 100 mg Trisoint and 35 mg Cytomel. I appreciate this forum and the participants with so much knowledge in many areas!<br><br>

@patreats5674, I think you would be interested in reading and taking part in this new discussion about thyroid and underlying conditions that @johnwburns just started.

Subclinical Hypothyroidism https://connect.mayoclinic.org/discussion/subclinical-hypothyroidism/

Thanks. I should have named the discussion something like "Thyroid disease's impact on other conditions" but I thought that that scope was too ambitious. Maybe I'll start another one.

35 mcg (not mg) is a lot of cytomel. Cytomel is 4:1 to levothyroxine so you are effectively taking 240 mcgs of T4. The average dose of T4 is 1.6 mcg/kilogram so I'd say you may be pushing the high end. If that is the case, controlling your BP with a high thyroid replacement load could be futile.

I can change the title of the other discussion if you like.

Yes, I thin you responded to some of my earlier inquires ... Thanks!

Hello John, <br>Thank you so much for your reply and good information. I don't know how to reply on the site. I hope I am not bombarding you with emails or if you are even getting them.<br>Thank you again<br><br><br>

Your welcome. You found me.
Just find a discussion and open it. My comments will show along with others. Or click on my handle and you'll see my comments.
I'm still learning this thing myself.
Another thing I'm wondering is why your doc put you on Tirosint since its so expensive. Do you have major absorption issues? Seems especially odd that its paired with so much Cytomel. Studies are suggesting that there are a minority of thyroid patients who need T3 to feel right but most do alright with levothyroxine if dosed properly. Things will influence that like your age and general health. Is your thyroid completely gone, as in ablated or removed?
Here's a calculator that's in beta mode but you might find it interesting.
http://www.globalrph.com/thyroid_calc.htm
One key term here is "lean body weight", Explained under "Ideal Body Weight". In other words the 1.6 or 1.7 mcg per kilogram replacement rule of thumb doesn't apply to your actual weight and someone who is very overweight should not be taking a huge replacement rose of thyroid.