Sedimentación Rate elevated, Proteína C Reactive elevated for 3 years

What kind of symptoms are you experiencing? That might help some other members in pointing you in a direction.

There are many things that can cause an increase in CRP and ESR. The one that pops into my head, only because I’m a caregiver for my father who has it, is Polymyalgia Rheumatica. It’s an inflammatory arthritis that causes severe pain and weakness in the large muscles, and fatigue. But it primarily affects older people, and that’s something a rheumatologist would probably consider if they suspected it.

Hopefully others may be able to chime in. Wishing you all the best. I know it’s tough.

Thanks for answering. I can tell you that extreme chronic fatigue even though I am sitting and pain all over me. body, shortness of breath, inability to stand for longer 25 minutes, overwhelming fatigue.

If you wanted to look into the condition I mentioned (PMR), here’s a Mayo Clinic link about it: https://www.mayoclinic.org/diseases-conditions/polymyalgia-rheumatica/symptoms-causes/syc-20376539

But it’s much less likely if you’re age 50 or younger, as it’s usually something that strikes people 65 and up.

There tends to be severe muscle pain in shoulders, core/abdominals, glutes, quads, the large muscles of your body.

If you have Polymyalgia Rheumatica, it usually responds very well to Prednisone. Were you ever prescribed corticosteroids to treat the inflammation?
PMR and its companion disorder Giant Cell Arteritis (GCA) can cause pain, extreme fatigue, malaise, and anemia. It's called the anemia of chronic inflammation and appropriate treatment with steroids resolves it. I had it with GCA and had no energy whatsoever.

When I had an attack that ended in neuroretinitis optica I They put in a lot of IVs of Prednisolone, that was at the beginning of my condition, however, no doctor has treated my inflammation, they are just looking for a cause. Thanks for answering.

The cause of PMR is not really known, although persons of Northern European ancestry develop it at higher rates than others, but it is important to treat the inflammation. So, if your symptoms were to respond to prednisone at the appropriate dosage for PMR, it's likely PMR. For GCA, there is a test, a biopsy of the temporal artery.

Have you been tested for Celiac Disease? I had suffered for 12 years with bouts of leg paralysis, ataxia, debilitating hip joint pain, anemia, etc. I had been treated many times with steroids which would help me to come out of those bouts... But then some other symptom would inevitably surface. I had seen so many specialists including multiple neurologists, endocrinologists and rheumatologist who tested me for Lyme, MS, Lupus etc and those always came back normal. They agreed that it had to be inflammatory... But it wasn't until a GP hospitalist tested me for Celiac Disease that we found the source of inflammation. There are so many reasons for a body to suffer from chronic inflammation... Celiac Disease is just one of many. But I have learned that approximately 50% of people who have Celiac Disease are either misdiagnosed or not diagnosed. Many doctors are just not aware of the non-digestive issues associated with this disease. Celiac Disease can mimick many other autoimmune diseases. It is tested at first with a simple blood test... If those results are questionable, then an endoscopy is done to biopsy the small intestine for a possible Celiac Diagnoses. In order to test for Celiac, you need to be consuming a gluten diet. My GI doctor recommended "Celiac Disease: the Hidden Epidemic" written by Dr. Peter Green... It was there that I found out that my symptoms, although uncommon, are just a few of the over 200 symptoms that Celiac Disease can cause. I do not know if this is at all helpful but I thought I would share in case you feel it could be something worth investigating. I am so sorry for all you are going through and hope you find answers and healing soon!

I appreciate your empathy and good wishes. My gastroenterologist performed those tests on me... I am not celiac. I need endoscopy/colonoscopy, however due to my pneumonitis and inflammation in the lungs I haven't been able to yet. Blessings, I very much appreciate your comment.

Blessings, my rheumatologist commented that I am only 47 years old for that condition...despite the chronic inflammation, extreme fatigue and everything in between...

I am glad to hear that you have been tested for this. Prayers that you find answers and healing quickly!