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Reclast Infusions: Side-effects & Recovery time

Osteoporosis & Bone Health | Last Active: 1 day ago | Replies (567)
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@rjd

Windy. Good to hear you are feeling better after the Reclast. Would you be so kind as to explain what the 'rebound' looks like when the medication you were taking was a bone-builder (Evenity) rather than an anti-resorptive like Prolia?

Is it the same sort of 'rebound' associated with Prolia, which I understand is a surge of osteoclastic cell activity that overwhelms the efforts of osteoblasts? Or is there something about the term 'rebound' that I do not understand?

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Replies to "Windy. Good to hear you are feeling better after the Reclast. Would you be so kind..."
windyshores | @windyshores | Jun 16 11:39am

@rjd I took Tymlos for two years and Evenity for 4 months. After either drug, I was told Reclast was necessary (I cannot take Fosamax due to GERD, and Reclast does a better job of coating the bones). The mechanism of "rebound" is not the same at all as with Prolia. In fact, though I have heard that term applied to all these situations, I would actually just say that without Reclast, I would lose my gains from the other two medications- I was told in two years. The term "rebound" is probably best used for Prolia discontinuation!

I honestly think that Evenity is too new for the doctors to really know, and more research needs to be done. Since it is anti-resoprtive, I have read they are looking into whether Evenity works without Reclast and also whether Evenity could be done for 6 months and Reclast could replace the last 6 months of Evenity. None of this is anywhere near clear yet>

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