It was pretty tough the first three days after the first round of chemotherapy. We went twice to the ER. Once for shortness of breath and next for constipation. That's all sorted out now and she takes Mirolax every day at noon. She has steadily improved. The next chemo session is Tuesday and a new chemical will make the session last 5 1/2 hours. The day before I get a squamous cell carcinoma removed from my right wrist, but that is routine for me and won't affect my driving. We're soldiering on with life.