Side effects with omeprazole/Prilosec use

My Gastro tried to convince me that it's the Over the Counter PPI's that are ONLY for 14 days ? That the studies people quote either were BLIND or not BLIND studies whatever she was trying to say but that my Colonoscopy & Edoscopy show NO signs of damage ?

@drsletmedown
Remember the OTC PPIs that are only recommended for 14 days started out as Hospital IV only. The research studies were obviously double blind - pointed out probably just to emphasize it was credible research. Or perhaps the research to the market was not double blind and she is saying it deserves to be discounted and dismissed. . In any event it was modified to pill form and put on the market initially as prescription only in the 80’s.
As one who stayed on Prilosec or Nexium for FOURTEEN YEARS and am paying the price now with microscopic colitis. And my colon didn't show damage either. Until I got symptoms and biopsies of the colon proved to be collagenous colitis.
Ive weaned off Both Ibuprofen and PPIs since both are
medication triggers for
Microscopic colitis - a horrendous condition. I was successfully treated with a colin-specific steroid but it still flares from time to time. I take pepcid for reflux.

So I’m a traveling preacher now, screaming to get off drugs that have a shelf Life of 14 days. 🙂

I hope thats useful.

Omg I do agree !! Please let me know what new Dr. says . I’m rooting for you .
Been another horrendous day here . Barely ate . The up 3 x this am . Then finally ate some dinner and had the worst of the 4 diarrheas of the day .
Heart ❤️ palps kicked up . Just misery all around.
Just a break once a week would be Amazing to me .
It never happens not in 11 years.
The sad thing is it’s only getting worse. I look 50 and I’m 62 but feel 100 .
Keep in touch 🙏

I'm NOT doing it NOW but before I did & my reg Gastro said same thing I DID do awhile back & it seemed to help other than sometimes went the other way & got stopped up. Take an Imodium every other day. I just took a half of one once a day. For nausea I use Emetrol it's cheap at Wally World & usually works in about 15 mins.

@drsletmedown
Remember the OTC PPIs that are only recommended for 14 days started out as Hospital IV only. The research studies were obviously double blind - pointed out probably just to emphasize it was credible research. Or perhaps the research to the market was not double blind and she is saying it deserves to be discounted and dismissed. . In any event it was modified to pill form and put on the market initially as prescription only in the 80’s.
As one who stayed on Prilosec or Nexium for FOURTEEN YEARS and am paying the price now with microscopic colitis. And my colon didn't show damage either. Until I got symptoms and biopsies of the colon proved to be collagenous colitis.
Ive weaned off Both Ibuprofen and PPIs since both are
medication triggers for
Microscopic colitis - a horrendous condition. I was successfully treated with a colin-specific steroid but it still flares from time to time. I take pepcid for reflux.

So I’m a traveling preacher now, screaming to get off drugs that have a shelf Life of 14 days. 🙂

I hope thats useful.

I've trying to slowly wean off pantoprazole. I've take it for 2.5 years, one year at 40mg then 20mg after that. Every few days, I substitute Pepcid 20mg twice a day instead. I've tried this before and wasn't successful. But like you, I have osteoporosis so really want to get off it. How did you transition and do you take only Pepcid now?

Can you share the steroid they used to treat your colitis? I’m desperate for help !

Emetrol doesn’t work for me . It’s just really sugar water if you read ingredients. I do take immodium if Diarrhea gets too much .
I tried RX of Verbazi but broke out in huge back rash and nausea within 10 days . It’s for IBS-D
Had to go off .
I just take Ultra Pepto daily 10 years now . Doesn’t help much anymore.
I can barely eat with all my symptoms now .
I’m getting worse each year.
Tried everything, did everything test . They know I have 8 diagnoses but can’t help me .
Thanks for response .

Short version of a long story. I'm male 71. My Gerd/Reflux started 30 years ago & I was given Prilosec 20mg daily & it worked. I've had EVERY issue I am NOW reading about as side effects & that it was only intended for 14 days ? I've been to Gastros & had colonoscopies & indoscopies as recent as June 2023 & numerous negative stool cultures & ASK for HELP from NUMEROUS Drs over the years to NO avail. I've been hospitalized several times with my diarrhea & low magnesium & NOW to ME it ALL is starting to make SENSE. My biggest concern is I'm muscle wasting & have had testing done & told NO muscle disease. ALL sorts of labs & blood work. CT & MRIs. I'm really getting a lot of loose skin ALL over. I'm weak 40 lbs feel like lifting 100lbs. Aches & pains pretty much everywhere. Hips & knees & shoulders. Have xrayed everything & all I get is you have Osteoarthritis. Offer up MORE pills. I feel like NO one will address it I think since they have continued prescibing it so long & NOW there is so much BAD about it that they are AFRAID to say anything ? My kidney labs are always out of range, borderline anemic & other labs are out of range & when you READ about what they CAN mean a lot lead back to cancer. It's SCARY to THINK this may be related to talking this medication but when I question several years of labs out of range I'm told its OK & expected for my AGE ? Spinal surgeon & Rheumatologist both said Spinal Stenosis in his opinion was causing it & surgery could supposedly stop or slow it but a 6 hr surgery & 3 month recovery sounds scary. ANYONE going through anything like this ? Occular migraines are more & more frequent too does any of THIS sound FAMILIAR to anyone on Omeprazole 20mg. long term? It works but if the drug ruins your quality of life why take it. I tried once to get OFF this & the rebound was awful. I've rotated every other day with Famotidine 20 mg but it falls shot by mid day the next day. Thinking about trying morning & night ? Drs really NO help. I see a lot of lawyers taking cases ? I just want my life BACK & a REAL fix.

Short version of a long story. I'm male 71. My Gerd/Reflux started 30 years ago & I was given Prilosec 20mg daily & it worked. I've had EVERY issue I am NOW reading about as side effects & that it was only intended for 14 days ? I've been to Gastros & had colonoscopies & indoscopies as recent as June 2023 & numerous negative stool cultures & ASK for HELP from NUMEROUS Drs over the years to NO avail. I've been hospitalized several times with my diarrhea & low magnesium & NOW to ME it ALL is starting to make SENSE. My biggest concern is I'm muscle wasting & have had testing done & told NO muscle disease. ALL sorts of labs & blood work. CT & MRIs. I'm really getting a lot of loose skin ALL over. I'm weak 40 lbs feel like lifting 100lbs. Aches & pains pretty much everywhere. Hips & knees & shoulders. Have xrayed everything & all I get is you have Osteoarthritis. Offer up MORE pills. I feel like NO one will address it I think since they have continued prescibing it so long & NOW there is so much BAD about it that they are AFRAID to say anything ? My kidney labs are always out of range, borderline anemic & other labs are out of range & when you READ about what they CAN mean a lot lead back to cancer. It's SCARY to THINK this may be related to talking this medication but when I question several years of labs out of range I'm told its OK & expected for my AGE ? Spinal surgeon & Rheumatologist both said Spinal Stenosis in his opinion was causing it & surgery could supposedly stop or slow it but a 6 hr surgery & 3 month recovery sounds scary. ANYONE going through anything like this ? Occular migraines are more & more frequent too does any of THIS sound FAMILIAR to anyone on Omeprazole 20mg. long term? It works but if the drug ruins your quality of life why take it. I tried once to get OFF this & the rebound was awful. I've rotated every other day with Famotidine 20 mg but it falls shot by mid day the next day. Thinking about trying morning & night ? Drs really NO help. I see a lot of lawyers taking cases ? I just want my life BACK & a REAL fix.