B-6 vitamin danger!

Posted by Lynsorensen @lynsorensen, Dec 11, 2017

With the assistance of a neurologist at Mayo Clinic, I have almost completely eliminated the uncontrolled muscle spasms now. First and foremost: beware of taking multi-vitamin capsules that have B6 listed. B-6 overdosage (which is contained in every multivitamin I found in stores and on the internet) can cause loss of muscle control and spasms in some people. So can gluten found in many foods so now I am also gluten free. I now work out with a personal trainer 3 days a week and do water aerobics another 2 days. Got off gabapentin and also clonazepam. Using CBD oil capsules each morning (no more opioids or chemicals) and using a CBD topical ointment to rub on my leg muscles each night. He says I don't need him anymore! And I don't. No more shaking or muscle cramps or pain. Still a little numbness but that is receding also.

Interested in more discussions like this? Go to the Neuropathy Support Group.

My neurologist prescribed B6 and Magnesium oxide…

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Can you share the brand of CBD oil?

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@johnbishop

Hello @linnythepoo - I love that user name! Welcome to Mayo Connect - I'm happy you found us. It is a great place to ask questions, share your health concerns and learn what others with similar health issues are doing for treatment. Yikes is right from my perspective but I have no medical training or background. I would want to get an opinion or see a neurologist first.

Have you received a diagnosis of a form of neuropathy from a neurologist or had any tests to confirm the diagnosis?

I had a roundabout discussion through a 3rd party who I asked to check out a list of supplements that I'm taking for my peripheral neuropathy and this person giving the opinion was a neurologist. They said meh to my supplements and said they would probably recommend Metanx which contains L-methylfolate calcium, an active form of folate, and other essential B vitamins (B6 and B12) instead. B12 is in my list of supplements but I had already heard some bad stuff about B6 so I filed her opinion away under the category - it's my body, my decision. It's really a good idea to learn everything you can about your health condition and any drug used for treatment paying close attention to any side effects. I don't have any medical training or background so this is just based on my opinion and how I've dealt with my own idiopathic small fiber peripheral neuropathy.

Here's a more reliable source from the University of Virginia Health System - Peripheral Neuropathy and Vitamin B6 (PDF):
https://cancer.uvahealth.com/images-and-docs/neuropathy.pdf
Hope this helps,
John

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I am surprised to hear that vitB6 has such a suspect history in connection with neuropathy. I checked several very well known supplements used for neuropathy and every one contained B6 of various amounts. I also checked my own Bcomplex and this too contained a small quantity. Where has the adverse info about B6 come from.

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@bigjohnscho

I am surprised to hear that vitB6 has such a suspect history in connection with neuropathy. I checked several very well known supplements used for neuropathy and every one contained B6 of various amounts. I also checked my own Bcomplex and this too contained a small quantity. Where has the adverse info about B6 come from.

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Here's some light reading 🙃

Vitamin B6 Toxicity Revisited: A Case of Reversible Pyridoxine-associated Neuropathy and Disequilibrium. (P4.021)
-- https://n.neurology.org/content/90/15_Supplement/P4.021

Vitamin B6 Toxicity
https://www.ncbi.nlm.nih.gov/books/NBK554500/
B6 section it explains -- too much or too little gives neuropathy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287/

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