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Does anyone else have MGUS?

Blood Cancers & Disorders | Last Active: 1 day ago | Replies (862)
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@menetski4

I was diagnosed with MGUS last summer concurrent with a thoracic vertebral compression fracture. In January I developed Polymyalgia Rheumatica (PMR). I wonder if MGUS is the chicken or the egg. How about others?

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junipergin | @juniperjgin | May 4 11:04pm

This is my own conundrum with conditions and symptoms AND the presence of MGUS.
Chicken or egg?
This is an unanswered question!

But, recent research is starting to show that MGUS with the presence of some rheumatological disease may cause an increased likelihood of progression to Multiple Myeloma or lymphoma.
(Instead of 1% the statistics are higher, but less than 10% annually.)

I apologize but I do not have links to studies handy. I printed several and deleted them.

I simply searched MGUS and rheumatological disease, as I pondered this chicken or the egg question.

Several studies came up and they are quite recent, all in the last several years.

I believe we have much to learn!

Meanwhile, some of us are living the consequences of MGUS, in my opinion, not being entirely “asymptomatic” for some of us and in other ways than are currently recognized (such as “renal significance”).

What is happening in our bodies?

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