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← Return to Ca25-29 and CA 15-3: One marker going up and the other down?
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Ca25-29 and CA 15-3: One marker going up and the other down?
Breast Cancer | Last Active: May 7, 2024 | Replies (12)Comment receiving replies
I had my first scan after being on verzenio and anastrozole for 3 months was very disappointed my scan shows my tumors grew a little blood my tumor markers CA-15-3 is declining drastically went from 119 to 60 and my CA 27-29 was 230 went down to 60 then back up to 113: I’m also doing the Signatera test and that has shown a steady decline. My question is this I’m confused the blood work shows a decline in tumor markers but the scan show a slight growth, is this normal has anyone experienced this .
Replies to "I had my first scan after being on verzenio and anastrozole for 3 months was very..."
Hi @shireen71, I'm sorry to hear about your disappointing scan after 3 months on Verzenio and anastrozole. I moved your post to your original discussion so that members can see a bit more of your diagnosis and journey.
Have you had a chance to speak with your oncologist in the meantime to get a better understanding of the different indicators that the tumor markers vs the scan seem to be saying? What did you learn? Has your treatment plan changed?
What do you mean by "the scans?" I ask because I am to have a CT scan with contrast on May 14th, never having had one. It was ordered after my LFT (Liver Function Test) numbers went off the charts from standard bloodwork.
I was feeling fine and thought the appointment with my Texas oncologist was just going to be a routine one before we leave Austin to return to the Midwest, but now I am being sent for a CT scan with contrast (abdomen and pelvis) and I wondered if the "scans" you mention in passing are those. Here is what they are supposedly going to be injecting me with on May 14 to get a look at the liver (and other) organs:
What Is Omnipaque?
Omnipaque (iohexol injection) is a radiographic contrast medium indicated for intrathecal administration in adults including myelography (lumbar, thoracic, cervical, total columnar) and in contrast enhancement for computerized tomography (myelography, cisternography, ventriculography).
What Are Side Effects of Omnipaque?
Common side effects of Omnipaque include:
headache,
mild to moderate pain including backache, neck ache and stiffness,
nerve pain,
nausea,
vomiting,
fever,
hives,
stomach upset or pain,
visual hallucinations, and
neurological changes.
Anybody have one of these and, if so, how was it?
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Hard to comment without knowing history: type of cancer, dx date, initial treatments, etc.