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MDS: Can someone explain how or why platelets go up or down quickly?

Posted by hlmcneely @hlmcneely, Sep 25, 2022

Can someone explain how or why platelets go up or down quickly. My diagnosis was MDS after a bone marrow biopsy and I was sent to a second specialist. Previous diagnosis was ITP. My question is how can platelets rise or drop within days. When I was sent for biopsy they were 64. Four days later 84. This past Tuesday 76 Friday 84. Thank you.

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suetex | @suetex | Apr 20 10:37am

I too, have MDS. My platelets go up and down too, but as yet they haven't gone so low as to cause a problem. Mostly I have low white and red cells and have recieved shots for both over time. This last go around I did feel the anemia and was weak for a few days. Haven't had to have any transfusions. The only thing that is high is my monocytes. 35% the last count. And they look normal. I am going to ask my oncologist if they are a problem, when I see him next. No professional has said anything about them. Still, I wonder....
I think my risk factor was the radiation I had for my breast cancer and a lip growth.

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alpinegirl | @alpinegirl | Apr 20 11:21am
In reply to @kathy115 "My husband also has mDS. He was considered mild but his levels are very low(platelets 24)..." + (show)
@kathy115

My husband also has mDS. He was considered mild but his levels are very low(platelets 24) and his rbc hovers around 8, when it gets to 7.6 he gets a transfusion. His doctor called it a blood disorder that can become leukemia. I’m surprised at how many people you know that also are diagnosed with it. Is it becoming more commonplace and what is causing the uptick? I sure wish I had the answers. The doctor is recommending another biopsy of the bone marrow. Best of luck to you.
Kathyt

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I came across an article that stated MDS can come from having stomach or intestinal surgery.
I had a growth removed from my colon approximately 1-1/2 to 2 years ago. The day before
surgery my hemoglobin was 13 and seven days later was 11.7 Finally went to the doctor after
finding myself breathles at times - a CBC showed my hemoglobin was down to 6. that was the
start of my blood transfusions and my diagonosis of MDS

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