Prolia and Evenity Together

Evenity can only be followed by Prolia or Reclast from what the endocrinologists say..one patient said or Fosamax…anyone hear of additional ones to follow 12 months of evenity?
( Prolia and Reclast have so much bad press…don’t know what to take)

I am on #9 of Evenity and my endo Md said she wants me to go on reclast after the Evenity not Prolia which I would never go on .

Best to listen carefully to reports from patients. Never dismiss them as "horror stories."
When you look at the trials, don't look at abstracts. Look at the studies themselves: how careful the patient selection is; how many patients had to quit the trials; how many actuals end up with their numbers on these neat little charts.
There is one chart reprinted (even here) that resulted from 14 patients, excluding 12 of the 37 originals.
Read the disclaimer on PubMed.
Keep in mind the need of academics to publish, the wealth of pharmaceutical industries. And then remember the generosity of patients here who tell their tragedies only to protect the rest of us.

Thanks for your input…I thought both were bisphosphonates and therefore have similar issues. Do you know what the difference would be? Would really appreciate why one is safer! I need to decide too and was leaning toward Reclast but my doc doesn’t care which one..but I
do.

Hi @gently - Thanks for responding. Of course individual treatment experiences are extremely valuable and I have learned a lot from those experiences. It is tough for a lot of people to share their stories and they are brave to do so.

From a reader perspective, one has to take all experiences with a grain of salt. When placebo adverse events are near equal to on drug events, you have to put everything into perspective. I have read and heard a lot of stories of people getting scared off of treatment just to have a spine or hip break a few years later, and then go on the drug they were scared off of in the first place.

I agree with you on reading trials thoroughly as the devil is in the details for these things. But if you are pushing a T-score of -4.5 and you get convinced that just changing the type of calcium you are taking is going to move the needle, you are headed for disaster.

Just based on what I have learned in the 20 short months since being diagnosed myself. 🙂

I agree it would be very difficult just changing calcium when you have a T score of -4.5 .
My spine T score is -4.6 and I fought off medications for 2 years and tried all types of natural modalities and now I am on Evenity .

Hi doreenr,

I have attended a lot of trainings on Osteoporosis treatments and none of the doctors are recommending taking Evenity and Prolia at the same time. Evenity, like Tymlos or Forteo, need some osteoclast action to be effective and Prolia really slows it down.

Without knowing your other factors like P1NP, CTX, PTH... that could influence treatment, Evenity has the best response in the shortest time and is the first choice for doctors to get you out of the high fracture risk zone. Like others has said here, Evenity followed by Prolia makes more sense, at least to me.

Good luck!

Mike

I am on evenity too and it’s one year is almost up…
now what? Do you have any info on the difference between Reclast and Prolia..any studies as I’d like to base it in facts.

I am on #9 of Evenity and my endo Md said she wants me to go on reclast after the Evenity not Prolia which I would never go on .