M-Spike, High Kappa and Kappa/Lambda Ratio
After experiencing chronic diarrhea for > four weeks, I decided to contact my gastro doctor. He ordered blood work and performed a colonoscopy and upper endoscopy with various biopsies. The colonoscopy, upper endoscopy and biopsies showed no sign of cancer or microscopic colitis, however the blood work showed a quite elevated IgA level. He referred me to a hematologist/oncologist who did further blood work, the results of which showed:
• Borderline low white blood count
• Borderline high red cell distribution width
• Low lymphocytes
• Low monocytes
And the most troublesome results:
• Kappa Free Light Chain Level: 290.7 mg/L, well outside of the 3.3-19.4 mg/L acceptable range
• Kappa/Lambda Ratio: 45, well outside of the .26-1.65 acceptable range
• IgA Level: 2111 mg/dL, well outside of the 70-400 mg/dL acceptable range
• IgG level of 698 mg/dL, barely outside of the 700-1660 mg/dL
• M-Spike: 1.29
There are other data points outside the reference ranges, but these are the ones that concern me most. I had been overseas when I received the results and asked my hematologist if I should cut my vacation short to come home for further evaluation/tests. He urged me not to do so and told me it can wait. I managed to enjoy my vacation but now that I returned I can't stop worrying. I'm following up with my hematologist to see what the next step is. I'm scared.
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Thanks. I was diagnosed 2 years ago and have been taking high dose Curcumin as well
Can you tell if it’s helped?
I can say my light chains did decrease a little. These are the two Curcumin I take. I also take some Omega 3 supplements with them.
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2 ReactionsHope you continue to do well. I go back in August for recheck and if stays stable or improves will go to yearly.
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1 ReactionHere is a video of Dr. Shah’s talk with the San Francisco Bay Area Myeloma Support Group. You can listen to the presentation and/ or download her slides.
Living Well With Myeloma: Can Nutrition Improve Quality of Life and Outcomes in Myeloma?
https://www.myeloma.org/videos/living-well-myeloma-can-nutrition-improve-quality-life-outcomes-myeloma
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3 ReactionsI had one MD ANDERSON WITH ONLY LOCAL lidocaine. It was practically painless. I’ve had dentist hurt me more! No driver needed after procedure.
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1 ReactionWell in that case, I’m out. No way I’m getting anymore vid shots. Only reason I took the two in the first place was under duress. And even then I took them 3 months apart not how they suggested
As my doctor said when I ventured the idea, we will know in 20-30 years when we have the data.
I think overall, the mRNA vaccines saved millions of lives, but for a few of us may not be a good risk/benefit.
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1 ReactionHealthtree Webinar
How to Optimize Your Health as a Myeloma Patient
Nutrition and Wellness for Myeloma
event
Mar 21, 2024 / 01:00PM - 02:00PM EDT
Healthtree.org
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1 ReactionSo, as I mentioned in another post, on or about March 12th I was scheduled for a bone marrow biopsy to take place on April 2nd. My hematologist/oncologist has not advised me to get bone scans or to undergo a 24-hour urine test - at least not yet. I don't understand why those tests cannot be done in parallel while I'm waiting to have the bone marrow biopsy done. Should I be concerned about this? Should I be more proactive and insistent with my hematologist/oncologist that these tests be done? Maybe there's a reason why he's waiting until after the biopsy to have me undergo these additional tests.
I want to be my own advocate, but I have no medical background and feel that I would be overstepping my bounds if I question the doctor.
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