Oxaliplatin is no walk in the park, advice for CAPOX regimen?

Posted by chinoomee @chinoomee, Mar 7 10:49pm

Just had first infusion today.
Felt fine and now hours later everything hurts ( numbness, tingling, muscle aches, muscle spasms upon sneezing in my jaw, muscle spasms across my eyes/temple upon tear production and of course upon water being just slightly cooler than room temp) how did you guys manage?

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Suggest you have the infusion nurse wrap your fingers and toes in ice packs during infusion. This really helps prevent cold sensitivity and peripheral neuropathy

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we are only on #3 today, but we've been doing room temperature or better all bevys and food. If he needs gloves to open fridge or pick up items (winter gloves). Extra room heaters and heated blankets. Not much to offer yet but this is how we've been handling so far. Also interested in other suggestions.

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@roywalton

Suggest you have the infusion nurse wrap your fingers and toes in ice packs during infusion. This really helps prevent cold sensitivity and peripheral neuropathy

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Really? Not warm stuff almost like making the fingers colder so it's not targeted?

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Not during infusion. The way it works is when the cold packs are applied it shrinks the capillary vessels in your fingertips and toes and reduces the concentration of oxaloplatin in those areas that is the cause of cold sensitivity and neuropathy after infusion give it a try it really worked for me

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Hi - My husband is really affected by the cold sensitivity. Just wanted more on the cold packs... you applied them to your fingertips and toes after the infusion? For how long and for how many days? Appreciate the tip. Thanks!

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@roywalton

Not during infusion. The way it works is when the cold packs are applied it shrinks the capillary vessels in your fingertips and toes and reduces the concentration of oxaloplatin in those areas that is the cause of cold sensitivity and neuropathy after infusion give it a try it really worked for me

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Oh thank you I will ask them next time.

This sounds like the same idea as how the cold caps work for hair?

Yes more cold After infusion would just send the pain to the moon lol

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No kidding! After the first infusion I reached for a pitcher the refrigerator and it felt like I was grabbing stainless steel at -20°.

The cold sensitivity got better but still dealing with very minor neuropathy in the left foot, 4 months after last infusion. Btw if you get palmer plantar skin peeling the product Urea 40 on Amazon worked the best! Has aspirin in it along with urea and it worked well

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@roywalton

Not during infusion. The way it works is when the cold packs are applied it shrinks the capillary vessels in your fingertips and toes and reduces the concentration of oxaloplatin in those areas that is the cause of cold sensitivity and neuropathy after infusion give it a try it really worked for me

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I wish I had known that when I had my chemo last year! Good to know moving forward.

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Again. Only wrap during the infusion of oxaliplatin. The cold temp shuts down the capillaries in toes and finger so less oxaliplatin "leaches" in surrounding tissues. This is what causes the issues. Hop this helps you....worth trying!

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The Capecitabine pills are just as rough as the Oxaliplatin. 5FU in this fashion is deemed tougher than the 5FU thru the port... but can be a more effective cancer killer. The cold capping for hair loss is useless (from all that I have talked to)... besides, hair grows back soon enough when done with treatments. But the cold gloves and socks have helped many that I have talked to by lessening neuropathy. Some just hold frozen plastic water bottles during the Oxaliplatin infusions.

Gary

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