@ykr I started Tymlos in January and took 22 doses. I had several side effects that I consulted with my Dr about. I took a month break from Tymlos, then on March 1 started again. One of the side effects was bloating that I attributed to the daily "gut" injections. I asked if the thigh was ok to inject and the doc said yes. I could not find any info online or from Radius health as to whether the thigh was acceptable for injection using Tymlos, so I called them just yesterday. They said that they had not performed any clinical trials using the thigh as an injection site, therefore could not say the thigh was an option for injection. But, they did say to follow Dr recommendation, so since my doc said the thigh is ok, I am using my thighs on a rotation basis. Thigh, abdomen, thigh abdomen kind of thing, so each leg and side of the my gut gets a break from daily impaling. Good luck on your journey!

For what it’s worth, my doc said sub-q injections could be given anywhere - even in the back of the arms - but is generally injected into the abdomen and thighs because of ease of administration. I used a chart to remind myself of the location of each dose so I didn’t overdo it. I had bruising and the occasional drop of blood, but after the first “jab” it gets easier. Cheers!