I have PCV and Jak 2 positive. At the moment I am seeing two oncologist one in Florida when I am there at a cancer Institute, and one up in Wisconsin when I am there. Neither one has mentioned taking any supplements at this time. I take 500 mg of hydroxy, three times a week, and a baby aspirin every morning. I’m lucky I feel like 1 million bucks. Until they bring it up I’m not going to upset the Apple cart.