I have experience with this very nasty skin condition. My mother-in-law had it in her 90’s, and my husband has it now. For about 8 months my husband was treated with doxycycline and topical steroids. This barely kept it under control. The miracle for him has been Dupixent. His skin has completely cleared up. I give him injections twice a month. The only drawback is that it can be very expensive, but I think there are ways to help pay for it. He has had no side effects from it. I would highly recommended looking into it. I hope this has helped. You have all my sympathy in dealing with this very difficult condition.