Concerned about the side effects of anastrozole

Posted by tinalove @tinalove, Jan 31, 2016

I completed all treatments for breast cancer but now I am supposed to take hormone blocker, named anastrozole. im concerned about the side effects. Has anyone here taken it and did anyone have hair loss?

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I lost my hair after 2nd treatment of chemo (Adriamycin / cyclophosphamide)

Laurie

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Thanks for the response. I wondered if the hair loss was due to Femura.

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@francine6829

Which drug or treatment caused your hair loss?

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@francine6829
I began losing my hair about a week or so following my first chemo infusion (paclitaxel aka taxol). Chemo lasted about three months, after which my oncologist suggested 50mg/day of Biotin to regrow my hair, fingernails, and toenails (yes, even my nails had gone toxic and lifted).

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@francine6829

Thanks for the response. I wondered if the hair loss was due to Femura.

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@ francine6829
Femara is one of the aromatase inhibitors. (I take anastrozole, for example.) One of the side effects of all of the AIs is hair thinning due to the reduction of circulating estrogen from an AI. Taking Biotin daily helps. Just stop taking the Biotin a few days before any thyroid blood tests as it affects the test assay.

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@francine6829

Was the biotin helpful?

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@francine6829
Yes, I think it has been helpful for both my hair and nails (all grew back, thick and glossy) and I haven't noticed much thinning in the meantime. AIs are hard on skin, however, and I haven't found something to help that, yet.

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I have been on Femura for 5 weeks and have not seen any hair thinning yet, but perhaps its too early. I did not have chemo, only surgery and radiation.

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A number of people have mentioned biotin, also known as vitamin B7, to help promote hair growth. Recently, I came across these articles:
- Biotin, marketed for hair and nails, could skew some medical test results, researchers warn https://www.cbc.ca/news/health/biotin-can-interfere-with-lab-tests-study-says-1.5051992
- The FDA Warns that Biotin May Interfere with Lab Tests: FDA Safety Communication https://www.fda.gov/medicaldevices/safety/alertsandnotices/ucm586505.htm

Here are some key points from the first article:
"It is known that biotin supplements can interfere with lab tests, resulting in false positive and false negative results on a wide range of clinically important tests."
"Health agencies, including the U.S. National Institutes of Health (https://ods.od.nih.gov/factsheets/Biotin-Consumer/), say there isn't enough evidence to support the claims that biotin improves hair, nails and skin, and that more research is required before it should be recommended for that purpose."

@elizm, did your doctor tell you about biotin possibly interfering with lab tests?

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@francine6829

Which drug or treatment caused your hair loss?

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i had hair thinning from anastrozole. I only noticed it after about 4 months On the drug.

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@elizm

@francine6829
Yes, I think it has been helpful for both my hair and nails (all grew back, thick and glossy) and I haven't noticed much thinning in the meantime. AIs are hard on skin, however, and I haven't found something to help that, yet.

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My doctor told me to try the Gold Bond lotions - they have some for extreme dryness.

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