I was wondering if it would be ok to take Lutein with beta-carotene

Posted by elio @elio, May 12, 2016

Hello. I was wondering if it would be ok to take Lutein supplement in combination with beta-carotene to treat the slight blurriness in my right eye. Will this be causing any interactions in the long run? I think I've read somewhere that 25000 IU is the maximum dosage an adult can take as a dietary supplement on a daily basis. I intend to take about half this value (10 000 IU from a beta carotene supplement and 2500 IU or so from spirulina or other whole food supplements)
What about the side effects (joints and bones pains, diarrhea, dizziness) and how accurate is the lung cancer thing? I am a very light smoker (I sometimes smoke about 2 cigarettes a day). Are there any other side-effects I should be aware of. Besides, should I supplement on zinc when taking high daily doses of copper (up to 10 mg)? Thanks!

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Great question @elio. Have you talked to your doctor or pharmacist about taking these supplements? In the meantime, I found some really good articles that I think you might find useful.
http://mayocl.in/1TRN2j0 This one from Mayo Clinic talks about eating for eye health.
http://1.usa.gov/1UWeP4i This article from the National Eye Institute summarizes a study that provides clarity on supplements for protection against blinding eye disease

Do you know the cause of the blurriness in your eye? How have you been managing your symptoms?

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Thank @aliskahan for your prompt answer. I really appreciate a lot sharing these relevant articles. Actually, I had a Lasik eye surgery about 2 years ago. Ever since, I've always had this feeling that one eye is better that the other, and in my case, the right eye was always a total loser. I even went to my doctor after the surgery for many routine checkups, but the answer was never satisfying. I just can't keep comparing both eyes to no avail. Also, I am a computer worker and my job requires a great deal of focus and concentration so this is so distracting and led me into beleiving that this has badly affected my productivity and performance. I will give the supplements a try because it might be of a great help for me and also because I have nothing to lose. However, the unpredictible interactions between Lutein and Beta Carotene are stopping me from proceeding any further. I just wanted to make sure that these two supplements, which I found combined in some brands, are totally safe and wouldn't do me any harm. Thanks

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@elio

Thank @aliskahan for your prompt answer. I really appreciate a lot sharing these relevant articles. Actually, I had a Lasik eye surgery about 2 years ago. Ever since, I've always had this feeling that one eye is better that the other, and in my case, the right eye was always a total loser. I even went to my doctor after the surgery for many routine checkups, but the answer was never satisfying. I just can't keep comparing both eyes to no avail. Also, I am a computer worker and my job requires a great deal of focus and concentration so this is so distracting and led me into beleiving that this has badly affected my productivity and performance. I will give the supplements a try because it might be of a great help for me and also because I have nothing to lose. However, the unpredictible interactions between Lutein and Beta Carotene are stopping me from proceeding any further. I just wanted to make sure that these two supplements, which I found combined in some brands, are totally safe and wouldn't do me any harm. Thanks

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@elio we took your questions to a Mayo Clinic pharmacist. Here some information that she gathered, much of it from the Natural Medicines Comprehensive Database http://naturaldatabase.therapeuticresearch.com/

"In general, lutein is rated as “likely safe” when taken orally and in proper amounts. Clinical trials have found it safe to take doses of up to 15 mg daily for up to 2 years. Lutein is considered “possibly effective” for treating age-related macular degeneration (AMD) and cataracts, and there is not enough reliable evidence to determine if it is effective for treating eye strain. With regard to reducing the risk of AMD, it is unknown if lutein supplements are as effective as dietary lutein. Studies focused on cataracts suggest that supplements and dietary lutein may both be beneficial.

There is an interaction between lutein and beta-carotene, but it is unpredictable in that beta-carotene may reduce OR increase the amount of lutein available in the body and lutein may reduce OR increase the amount of beta-carotene available.

Beta-carotene is considered “likely safe” for certain conditions, but is not recommended for use in the general population. Even low doses have been associated with increased risk of lung and prostate cancer in people who smoke. In fact, taking 20-30 mg daily may increase the risk of lung cancer by 18 to 28% in smokers (especially those smoking more than 20 cigarettes per day), former smokers, those who have had a history of asbestos exposure, and heavy alcohol drinkers. This risk seems to be specific to beta-carotene as a supplement, not the beta-carotene found in foods. Taking beta-carotene in combination with vitamin C, Vitamin E and zinc may reduce the progression of AMD. It is considered “possibly ineffective” for cataracts.

In general it seems that with any history of smoking, it would be best to avoid beta-carotene supplements and eat foods rich in beta-carotene instead.

Copper in doses up to 10 mg per day appears to be safe and tolerable for adults. Higher doses have been shown to cause liver damage. Zinc inhibits copper absorption and is used in certain patient populations to help the body eliminate excess. If using copper as a supplement in the recommended daily amount (10 mg or less), there should not be a need to also use zinc."

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@elio

Thank @aliskahan for your prompt answer. I really appreciate a lot sharing these relevant articles. Actually, I had a Lasik eye surgery about 2 years ago. Ever since, I've always had this feeling that one eye is better that the other, and in my case, the right eye was always a total loser. I even went to my doctor after the surgery for many routine checkups, but the answer was never satisfying. I just can't keep comparing both eyes to no avail. Also, I am a computer worker and my job requires a great deal of focus and concentration so this is so distracting and led me into beleiving that this has badly affected my productivity and performance. I will give the supplements a try because it might be of a great help for me and also because I have nothing to lose. However, the unpredictible interactions between Lutein and Beta Carotene are stopping me from proceeding any further. I just wanted to make sure that these two supplements, which I found combined in some brands, are totally safe and wouldn't do me any harm. Thanks

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@aliskahan thanks a lot! Are the interactions between lutein and beta-carotene major or minor? Would it be safer to supplement on both in order to avoid any deficiency that might occur in the future? Also, how much zinc, copper, and carotenoids -beta-carotene and lutein- in pumpkin seed oil? Is it okay to take 2 g of pumpkin seed oil daily along with 25000 iU (15 g) of beta-carotene? As I mentioned earlier, I'm a very light smoker (2-3 cigarettes per day, sometimes I do not smoke at all). Is there any possibility a/o evidence that supplementing with beta-carotene will affect my lungs in the long run? Besides, is it safe to take 40 mg of niacin (vitamin B3) which is found in a particular multivitamin along with red yeast rice? I've read that major interactions may occur when daily dosages of >=1 g of niacin are taken daily with 20+ mg of statins. Thanks!

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@elio

Thank @aliskahan for your prompt answer. I really appreciate a lot sharing these relevant articles. Actually, I had a Lasik eye surgery about 2 years ago. Ever since, I've always had this feeling that one eye is better that the other, and in my case, the right eye was always a total loser. I even went to my doctor after the surgery for many routine checkups, but the answer was never satisfying. I just can't keep comparing both eyes to no avail. Also, I am a computer worker and my job requires a great deal of focus and concentration so this is so distracting and led me into beleiving that this has badly affected my productivity and performance. I will give the supplements a try because it might be of a great help for me and also because I have nothing to lose. However, the unpredictible interactions between Lutein and Beta Carotene are stopping me from proceeding any further. I just wanted to make sure that these two supplements, which I found combined in some brands, are totally safe and wouldn't do me any harm. Thanks

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I recommend that you talk to your physician for informed answers about how these supplements may interact for your personal situation, given your lifestyle and medications. Before taking supplements it's always wise to discuss with your primary care provider. If you do speak with your physician, I'd love to hear what you find out.

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