Ethnic Differences in Liver Transplant Outcomes Among Adults With Primary Sclerosing Cholangitis

Feb 1, 2021 | Konstantinos N. Lazaridis, M.D. | @klazaridis

Absence of medical therapy for primary sclerosing cholangitis (PSC) leads to end-stage liver disease requiring liver transplantation (LT). However, studies specifically evaluating whether ethnic disparities in LT outcomes exist are limited. In a recent study published in the Journal of Liver Transplantation, Bayable et al., retrospectively evaluated US adults with PSC listed for LT between 2005-2017 using the United Network for Organ Sharing database. Among 4,046 patients with PSC listed for LT (69.2% men, 82.2% non-Hispanic white, 12.4% African American, 3.9% Hispanic, 1.6% Asian), significantly higher risk of waitlist death was seen in men vs. women, but no ethnicity-specific differences were noted. Compared with non-Hispanic whites, Hispanics had significantly lower probability of receiving LT. Among patients with PSC and end-stage liver disease who underwent LT, African Americans had significantly higher risk of post-LT death compared with non-Hispanic whites. The study concluded that significant ethnicity-specific disparities in LT outcomes were observed.

Read the paper by Dr. Bayable

Interested in more newsfeed posts like this? Go to the Primary Sclerosing Cholangitis (PSC) blog.

Please sign in or register to post a reply.