Study finds unique form of immunosuppression caused by brain cancer

Dec 19, 2020 | Jennifer O'Hara | @jenohara


The latest direction in cancer treatment has been toward potential cancer vaccines and immunotherapies. As these therapies become standard, continued research is important to understand how the body interacts with these treatments. A recent Mayo Clinic study found a unique form of immunosuppression caused by brain cancer that could inhibit the effectiveness of cancer vaccines and immunotherapies. The findings were recently published in the journal, Brain.

On the Mayo Clinic Q&A podcast, Dr. Aaron J. Johnson, a professor of immunology at Mayo Clinic, and Dr. Katayoun (Kathy) Ayasoufi, a research associate in Dr. Johnson's lab in the Department of immunology, discuss the importance of basic science research and explain how understanding the immunosuppression caused by brain cancer could lead to improved treatments for patients.

To practice safe social distancing during the COVID-19 pandemic, this interview was conducted using video conferencing. The sound and video quality are representative of the technology used. For the safety of its patients, staff and visitors, Mayo Clinic has strict masking policies in place. Anyone shown without a mask was recorded prior to COVID-19 or recorded in an area not designated for patient care, where social distancing and other safety protocols were followed.

Information in this post was accurate at the time of its posting. For more information, go to the Mayo Clinic News Network and

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