Overview of the Brain with Alzheimer's Disease

Jun 6, 2023 | Dr. Melanie Chandler, HABIT FL Director | @drmelaniechandler | Comments (1)

Towards the beginning of a HABIT session, I lead a discussion about the brain.  I give an overview of how the brain works, and we talk about how to understand what is happening in the brain in MCI and common causes of neurodegeneration.  There is one slide in particular where I take a "deep dive", as if looking in a microscope, to talk about what commonly is happening at a cellular level in Alzheimer's disease, Lewy Body Disease, Vascular Cognitive Impairment, and others.  It usually generates a lot of questions and great discussion.  It helps folks get a general idea of why they may be seeing the symptoms they are seeing and what the medications out there are for.

I recently was on the Alzheimer's Association's web-site looking at their stance on the newest amyloid treatment (see Dr. Locke's recent post on donanemab), when I came across a detailed explanation of the brain and brain changes in Alzheimer's disease.  It reminded me of this discussion we have in session, but they had way cooler graphics.  Check it out below:


While it really doesn't go into the explanations about brain-behavior relationships we talk about in HABIT, it is an easy to read, plain-language explanation of how the disease itself works in the brain.


Hope you find it educational!

Interested in more newsfeed posts like this? Go to the Mild Cognitive Impairment (MCI) blog.

Well done... short and very interesting / educational.



Thanks for the information. I developed Minor Cognitive Impairment after I used an ECT treatments (2). I was sent to a hospital clinic that performed long tests to determine the severity of your impairment.
I can’t remember the previous paragraph when reading a book but it was determined that my cognitive impairment was the result of depression medication I was on. I past the test twice in two years so it was nice to know I wasn’t going senile. They have tests developed to determine how impaired you are.

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