Liver Cancer: Research

Research programs of Mayo Clinic Comprehensive Cancer Center

Designated as a comprehensive cancer center by the National Cancer Institute, Mayo Clinic Comprehensive Cancer Center is defining new boundaries in possibility, focusing on patient-centered care, developing novel treatments, and bringing cancer research to communities.

The Cancer Center has a robust profile of discovery that has pushed out the horizon of hope. Among our exciting research success stories:

• Advancing CAR-T cell therapy, enabling Mayo Clinic to become one of the first centers in the U.S. offering CAR-T cell therapy as a clinical treatment. Learn about the CAR-T Cell Therapy Program.
• Driving research behind the Proton Beam Therapy Program at Mayo Clinic, which exclusively features intensity-modulated proton beam therapy with pencil beam scanning. Learn about the program.

• Developing Cologuard, the stool DNA test co-developed by Mayo Clinic and Exact Sciences Corp. and now a colorectal cancer screening tool recommended by the U.S. Preventive Services Task Force. Read more about the stool DNA test.
• Leading the International Duration Evaluation of Adjuvant Chemotherapy (IDEA) collaboration study, which showed that for patients with low-risk stage III colon cancer, a shortened course of oxaliplatin-based chemotherapy after surgery was associated with reduced side effects compared with the traditional course of chemotherapy and was just as effective.
• Demonstrating through the Breast Cancer Genome-Guided Therapy (BEAUTY) study that the most common genetic changes were not more commonly observed in chemotherapy-resistant tumors compared with chemotherapy-sensitive tumors. Read more about the study.
• Creating a new approach to classifying gliomas, led to the development of a test that helps oncologists determine who needs to be treated more aggressively and who might be able to avoid certain therapies. Learn more about brain cancer genomics.

With campuses in Phoenix/Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota, Mayo Clinic Comprehensive Cancer Center has a broad geographic reach, enabling it to serve diverse patient populations around the world.

Specialized Programs of Research Excellence (Spore) Grants

The National Cancer Institute (NCI) established the Specialized Programs of Research Excellence (SPORE) in 1992 to promote interdisciplinary research and to help basic research findings move quickly from the laboratory to the patient.

Mayo Clinic Comprehensive Cancer Center has four NCI SPORE grants including Hepatobiliary cancer.

• Learn about ongoing and upcoming clinical trials, including a study of MTI-301 in patients with advanced malignancy.
• Building on significant contributions to science, the SPORE has four translational research projects that focus on hepatobiliary cancer.
• Contact us about research projects or learn about our funding awards and training opportunities for qualified women, people of color, people with disabilities, and other promising researchers.