Study opportunity: Seeking volunteers with type 2 diabetes and painful peripheral neuropathy

Jan 28, 2020 | Narayan R. Kissoon, M.D. | @narayanrki | Comments (10)

2020_2_18 Spinal Cord Stimulator

Quantitative Assessment of Painful Diabetic Peripheral Neuropathy after High Frequency Spinal Cord Stimulation: (QUANT) HF10 Study Seeking volunteers with Type 2 Diabetes and painful peripheral neuropathy

Principal Investigator: Dr. Narayan Kissoon

IRB #17-004317

The Mayo Clinic pain clinic in Rochester, MN is seeking volunteers with type 2 diabetes and painful lower extremity peripheral neuropathy.  We are conducting research on the use of a spinal cord stimulator and whether it can improve nerve function.  Spinal cord stimulation (SCS) is already FDA approved for treatment of intractable neuropathic (nerve) pain related to diabetic peripheral neuropathy.  A screening visit which would take about 1 hour is required to make sure you are eligible.

If you are eligible, it will take about 1 year to complete this research study. During this time, we will ask you to make 3 study visits to Mayo Clinic in Rochester, MN (1 initial visit, 1 visit at 6 months, and 1 visit at 12 months). In between the on-site visits you will be contacted via telephone to review your progress. Remuneration is offered after completion of the study at 6 months and again at 12 months.

For more information, please contact the study coordinator at 507-422-0582 or Stoltenberg.Anita@mayo.edu

 

Connect with other patients talking about living with neuropathy in the Neuropathy Support Group.

Is the use of the Spinal Cord Stimulation new for neuropathy patients? I thought this system had already been used successfully for pain associated with the spinal cord.

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@camil1957

Is the use of the Spinal Cord Stimulation new for neuropathy patients? I thought this system had already been used successfully for pain associated with the spinal cord.

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Hi @camil1957, welcome to Mayo Clinic Connect. You ask a very good question. The physician-researchers of this study explain:

“You are correct in that spinal cord stimulation has been successful in treating neuropathic (nerve related) pain for over 30 years. Newer programming settings have recently come out for the spinal cord stimulators that seem to work better than the older systems and we are looking to see the impact these new settings have on the health of the nerves.”

Camil, might I ask, do you live with neuropathic pain? If yes, you may be interested in joining the discussions with other members of Mayo Clinic Connect in the Neuropathy group here: https://connect.mayoclinic.org/group/neuropathy/

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I have severe lumbar stenosis and osteoarthritis. I am also DM 2, with stage 4 CKD. The lumbar pain is debilitating frequently. I have a slight amount of numbness in my left foot and neuropathy in both thighs. Would I be a candidate for this procedure? Thank you very much. P.S. I also have 2 autoimmune diseases — giant cell Arteritis and polymyalgia rheumatica and am on a fairly low dose of prednisone (6 mg.)

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@valb68

I have severe lumbar stenosis and osteoarthritis. I am also DM 2, with stage 4 CKD. The lumbar pain is debilitating frequently. I have a slight amount of numbness in my left foot and neuropathy in both thighs. Would I be a candidate for this procedure? Thank you very much. P.S. I also have 2 autoimmune diseases — giant cell Arteritis and polymyalgia rheumatica and am on a fairly low dose of prednisone (6 mg.)

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@valb68, please contact Anita, the study coordinator to verify your eligibility for the study. You can reach her at 507-422-0582 or Stoltenberg.Anita@mayo.edu
Thank you for your interest in this research.

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@colleenyoung

@valb68, please contact Anita, the study coordinator to verify your eligibility for the study. You can reach her at 507-422-0582 or Stoltenberg.Anita@mayo.edu
Thank you for your interest in this research.

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I have been diagnosed with idiopathic neuropathy. Why do researchers mandate that study participants have diabetic neuropathy! A huge percentage of neuropathy patients have idiopathic disease. I would LOVE to participate in a neuropathy study but I am shut out because it’s idiopathic! It’s very, very, frustrating!

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What do you take? I find Amitriptyline works well. 25mgs to 50mgs. Keeps it from waking me up.

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@magnum52

I have been diagnosed with idiopathic neuropathy. Why do researchers mandate that study participants have diabetic neuropathy! A huge percentage of neuropathy patients have idiopathic disease. I would LOVE to participate in a neuropathy study but I am shut out because it’s idiopathic! It’s very, very, frustrating!

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@magnum52, You may wish to review the NIH's clinical trial listings. Currently there are 13 trials specifically research idiopathic neuropathy that I could find. There may be more. See this search result: https://www.clinicaltrials.gov/ct2/results?cond=idiopathic+neuropathy&term=&cntry=&state=&city=&dist=

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Thank you … I don't qualify for any of them but some of our members might … Peggy

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Hello , I just became registered, I was trying to get all my info to the mayo clinic , but was lacking a MRI, to follow up. My fault , any way, mu situation has changed . I had my left hip replaced, after that , about 6 months later my right knee was completely gone .Take into consideration my right foot was re constructed .
Just recently I had the Dr. take the heard wear out .I have about 10 days before my right knee is getting replaced. My feet are terrible with buzzing , numbness, and pin sticking , like the worse case of athletes feet u could have . When they took the hard wear out they used some type of numbing medicine , wich felt ok , the pain was gone, slowly it is coming back ,Does any one know what they use and were it is injected ?
There must be thing they can do for this . I own a business , and I’m not ready to lay down yet .

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@glassguy3

Hello , I just became registered, I was trying to get all my info to the mayo clinic , but was lacking a MRI, to follow up. My fault , any way, mu situation has changed . I had my left hip replaced, after that , about 6 months later my right knee was completely gone .Take into consideration my right foot was re constructed .
Just recently I had the Dr. take the heard wear out .I have about 10 days before my right knee is getting replaced. My feet are terrible with buzzing , numbness, and pin sticking , like the worse case of athletes feet u could have . When they took the hard wear out they used some type of numbing medicine , wich felt ok , the pain was gone, slowly it is coming back ,Does any one know what they use and were it is injected ?
There must be thing they can do for this . I own a business , and I’m not ready to lay down yet .

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Hi Glassguy, I see you received a response to your questions here https://connect.mayoclinic.org/comment/638835/

Have you contacted your surgeon who removed the hardware to know what anesthetic (numbing medicine) was used for you?

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