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Comments (1,094)

I did gradually go up in dosage from 20 mg Duloxetine to a max of 120mg...

https://connect.mayoclinic.org/comment/218602/

gradually go up in dosage from 20 mg Duloxetine ... compounded with my withdrawal from Duloxetine

Discussion: What are the symptoms of Cymbalta withdrawal?

Support Group: Depression & Anxiety

Posted: Jul 2, 2019

Hello d13. I have been on Cymbalta for eight years. I now take twice as much...

https://connect.mayoclinic.org/comment/683548/

medications you take may interact with duloxetine

Discussion: What's your experience with duloxetine (US Brand Name; Cymbalta)?

Support Group: Depression & Anxiety

Posted: Feb 22, 2022

I HAVE HAD OXCARBAZEPINE 300MG TEGRETOL -XR 100MG DULOXETINE DR 600 MG BEEN TO SPECIALIST HE...

https://connect.mayoclinic.org/comment/105858/

OXCARBAZEPINE 300MG TEGRETOL -XR 100MG DULOXETINE

Discussion: Trigeminal Neuralgia*

Support Group: Brain & Nervous System

Posted: Oct 4, 2016

@jetsetter I have been on Gabapentin for about a year now, We've gone from 900mg 3xday...

https://connect.mayoclinic.org/comment/675863/

over time and then further to 120mg Duloxetine

Discussion: How long do you take Gabapentin?

Support Group: Chronic Pain

Posted: Jan 28, 2022

Got PN one week after 2nd Moderna COVID booster. Am going to get my B12 levels...

https://connect.mayoclinic.org/comment/960545/

I am on Duloxetine which controls it

Discussion: 2023 flu shot, COVID booster and neuropathy

Support Group: Neuropathy

Posted: Nov 7, 2023

It works for me. I was a long time Gabapentin and Lyrica (Pregabalin) user and needed...

https://connect.mayoclinic.org/comment/1104037/

Duloxetine (Cymbalta) is a powerful ... Overall duloxetine has proven to be

Discussion: Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Support Group: Chronic Pain

Posted: Jul 12, 2024

guess I'll weigh in...My non diabetic neuropathy probably stems from alcohol abuse. And abuse it I...

https://connect.mayoclinic.org/comment/1225900/

3x day, eventually switched me to duloxetine ... B complex with the duloxetine. so I

Discussion: Neuropathy pills: How to avoid scams?

Support Group: Neuropathy

Posted: Jan 31, 2025

I was diagnosed with fibro many years ago. So, I've managed the pain with Duloxetine and...

https://connect.mayoclinic.org/comment/1429015/

So, I've managed the pain with Duloxetine

Discussion: Curious what medication to discuss with doctor regarding fibromyalgia

Support Group: Fibromyalgia

Posted: Nov 2, 2025

I have peripheral neuropathy due to cauda equina syndrome chronic incomplete. I gave numbness, saddle numbness,...

https://connect.mayoclinic.org/comment/877834/

not on opioids but on gabepentin and duloxetine

Discussion: Looking to connect with people who have non-diabetic neuropathy

Support Group: Neuropathy

Posted: Jun 13, 2023

You said , "Do not start it..." But we need to remember that every single person...

https://connect.mayoclinic.org/comment/1301403/

I am like @ams - duloxetine gave me ... What do you use in place of duloxetine

Discussion: Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Support Group: Chronic Pain

Posted: May 10, 2025

Good evening @dmoreci. It is great to welcome your post on this subject. I also take...

https://connect.mayoclinic.org/comment/953899/

I also take Duloxetine......and have

Discussion: Correlation between increased neuropathy pain and fluid retention?

Support Group: Neuropathy

Posted: Oct 25, 2023

Thanks, Steve. I also started my medications for SFN the very same way 11 years ago....

https://connect.mayoclinic.org/comment/1011601/

I increased the Cymbalta (Duloxetine

Discussion: Driving with Numb Feet.

Support Group: Neuropathy

Posted: Feb 8, 2024

I take 2 150mg of Pregabalin/Lyrica every night at bedtime. It does help with pain, but...

https://connect.mayoclinic.org/comment/1187141/

I also have RA and I am on 60mg of Duloxetine

Discussion: Lyrica / Pregabalin: What dose helps you with Fibromyalgia pain?

Support Group: Fibromyalgia

Posted: Dec 9, 2024

I exercise daily do deep tissue massage take vitamins and eat healthy. Currently on Pregabalin 150...

https://connect.mayoclinic.org/comment/660791/

Pregabalin 150 mg twice daily plus Duloxetine

Discussion: Anyone had a problem with neuropathy after receiving the vaccine?

Support Group: Neuropathy

Posted: Dec 8, 2021

@celia16 Hope you are not in the middle of this snowstorm. We had about 6 inches...

https://connect.mayoclinic.org/comment/1490234/

My primary care agreed to try me on duloxetine

Discussion: Salty tast in my mouth from diagnosed with Sjogren's

Support Group: Autoimmune Diseases

Posted: 13 hours ago

my doctor put me on a low dose of Duloxetine ( Cymbalta) which has reduced the...

https://connect.mayoclinic.org/comment/1254656/

my doctor put me on a low dose of Duloxetine

Discussion: Looking for recommendations to find relief for foot pain due to neurop

Support Group: Neuropathy

Posted: Mar 10, 2025

I switched from Wellbutrin to 60mg Duloxetine approximately 2 years ago for severe depression. I was...

https://connect.mayoclinic.org/comment/1145452/

I switched from Wellbutrin to 60mg Duloxetine

Discussion: What's your experience with duloxetine (US Brand Name; Cymbalta)?

Support Group: Depression & Anxiety

Posted: Sep 22, 2024

I’ve been on Duloxetine and Gabapentin, for about 2 years and Hydrocodone for a few months...

https://connect.mayoclinic.org/comment/1105944/

I’ve been on Duloxetine and Gabapentin ... I had the doctor change Duloxetine from

Discussion: Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Support Group: Chronic Pain

Posted: Jul 15, 2024

Sorry to hear about your wife's troubles. My neuropathy is serious but nothing on that scale....

https://connect.mayoclinic.org/comment/91459/

listed was an antidepressant, usually duloxetine ... www.ncbi.nlm.nih.gov/pubmed/23986501 Duloxetine

Discussion: Anyone here dealing with peripheral neuropathy?

Support Group: Neuropathy

Posted: Apr 28, 2016

Good morning @sf2021, Good for you. You are using good questions and following up on the...

https://connect.mayoclinic.org/comment/596275/

I substituted 60 mg of duloxetine (Cymbalta ... Two weeks ago, we added 30mg more of duloxetine

Discussion: Idiopathic Small Fiber Neuropathy - chest pressure/tighteness

Support Group: Neuropathy

Posted: Apr 22, 2021