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Comments (2,477)

Hi John, you are correct, it is not uncommon to misdiagnose PMR. This is my story......

https://connect.mayoclinic.org/comment/1263934/

tried to wean the prednisone and added methotrexate

Discussion: Surprised and Uncertain: Should I get a second opinion?

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Mar 22, 2025

I can relate to much of it ... I was diagnosed with ax-SpA about 35 years...

https://connect.mayoclinic.org/comment/1050543/

and not recommended with prednisone Methotrexate

Discussion: Question about PMR in addition to other autoimmune disorders?

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Apr 14, 2024

Interesting paper about IL-6 and inflammatory diseases The Two-Faced Cytokine IL-6 in Host Defense and Diseases...

https://connect.mayoclinic.org/comment/975917/

and immunosuppressive drugs, such as methotrexate

Discussion: PMR Dosages and Managing Symptoms

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Dec 6, 2023

I was recently diagnosed with immune-mediated necrotizing myopthy (IMNM) November 2022. Which was brought on by...

https://connect.mayoclinic.org/comment/810079/

mentioned the following azathioprine or methotrexate

Discussion: Statin Induced Rhabdomyolysis or Myositis Disorder

Support Group: Bones, Joints & Muscles

Posted: Feb 11, 2023

I was recently diagnosed with immune-mediated necrotizing myopthy (IMNM) November 2022. Which was brought on by...

https://connect.mayoclinic.org/comment/799540/

mentioned the following azathioprine or methotrexate

Discussion: Statin Induced Rhabdomyolysis or Myositis Disorder

Support Group: Bones, Joints & Muscles

Posted: Jan 21, 2023

Hi everyone, I am posting here in the hopes that someone has experienced something similar and...

https://connect.mayoclinic.org/comment/245100/

After a month, she was placed on methotrexate

Discussion: Hearing Loss: Come introduce yourself and connect with others

Support Group: Hearing Loss

Posted: Jan 17, 2020

Oh my god! Yes! I have asymptomatic pulmonary sarcoidosis. It was an incidental finding on a...

https://connect.mayoclinic.org/comment/921248/

prednisone which only made me sick, methotrexate

Discussion: Did PAXLOVID also relieve your arthritis and autoimmune symptoms?

Support Group: Post-COVID Recovery & COVID-19

Posted: Aug 29, 2023

@nanniepie, @tuckerp and all... Well. welcome to reality and our new world of crazy medical surprises...

https://connect.mayoclinic.org/comment/1215538/

of 8 mg Prednisone daily and 7.5 mg Methotrexate

Discussion: Aging

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Jan 18, 2025

I was diagnosed with PMR in Dec2020, tested negative for Covid, but then got sicker and...

https://connect.mayoclinic.org/comment/1366437/

lowered prednisone to 5mg daily with Methotrexate

Discussion: Anyone successfully treating PMR without Prednisone?

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Aug 8, 2025

Let me begin by saying I know how profound the loss of your husband is to...

https://connect.mayoclinic.org/comment/1084464/

missing from what I took originally was Methotrexate

Discussion: Neuropsychiatric Lupus

Support Group: Autoimmune Diseases

Posted: Jun 10, 2024

For perspective, I am a 54 year old woman with intermittant high blood pressure of unknown...

https://connect.mayoclinic.org/comment/1072256/

There are treatments: steroids, methotrexate

Discussion: Recommendation on When Should I have the Operation

Support Group: Aortic Aneurysms

Posted: May 21, 2024

We live in NE Arkansas. My 38 year old son had a T2 to L3 back...

https://connect.mayoclinic.org/comment/950570/

In 2017 they started him on methotrexate

Discussion: Ankylosing spondylitis: anyone else?

Support Group: Spine Health

Posted: Oct 19, 2023

No, you are not crazy. It isn't "you". Sometimes it isn't even the doctors. I posted...

https://connect.mayoclinic.org/comment/1022707/

So, Methotrexate was up.

Discussion: Lupus or not Lupus?

Support Group: Autoimmune Diseases

Posted: Feb 25, 2024

Wow, an MCTD group! Long-term survivor here, 66 years old, diagnosed in 1972. Initial treatment was...

https://connect.mayoclinic.org/comment/951102/

tells me, "Yeah, Plaquenil or Methotrexate

Discussion: MCTD (Mixed Connective Tissue Disease)

Support Group: Autoimmune Diseases

Posted: Oct 20, 2023

@joanmm Covid woke up my PMR I take methatrexate because pred has bad side effects for...

https://connect.mayoclinic.org/comment/1449989/

joanmm Covid woke up my PMR I take methatrexate

Discussion: Pain in legs with PMR

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Nov 30, 2025

@loribmt, and all... Hello, my Connect friend, Lori! Good to connect with you after such a...

https://connect.mayoclinic.org/comment/1036527/

I'm taking Prednisone, Methotrexate

Newsfeed Post: Colonoscopy prep: make it easier

Blog: Aging & Health: Take Charge

Posted: Mar 19, 2024

I'm heartbroken for you. I'm a former Brit living in the US so I remember the...

https://connect.mayoclinic.org/comment/1398789/

started with Sulfasalazine, then added Methotrexate

Discussion: Please help seronegative inflammatory arthritis

Support Group: Autoimmune Diseases

Posted: Sep 22, 2025

Hi Meredith, I have the identical symptoms that you have. My problems began at 30 with...

https://connect.mayoclinic.org/comment/73366/

my doctor is still pushing the drug Methotrexate

Discussion: Would like to hear from people with Sjogrens

Support Group: Autoimmune Diseases

Posted: Jun 22, 2012

PFIZER COVID-19 Vaccine and Rheumatoid Arthritis Onset (2021 through 2025) Any evidence so far linking COVID-19...

https://connect.mayoclinic.org/comment/1223272/

Alendronate, then Leflunomide, then Methotrextate

Discussion: Rheumatoid Arthritis (RA) - Introduce yourself and meet others

Support Group: Autoimmune Diseases

Posted: Jan 27, 2025

I have a rare autoimmune disease called lichen planopilarias, it started with firey itching and the...

https://connect.mayoclinic.org/comment/713563/

usually they treat with Plaquenil and Metotrexate

Discussion: What helps with hair loss?

Support Group: Just Want to Talk

Posted: Jun 2, 2022