Welcome to the online home of the Chris M. Carlos and Catherine Nicole Jockisch Carlos Endowment for Primary Sclerosing Cholangitis (PSC). Thanks to support provided by this endowment, dedicated Mayo Clinic investigators and their teams are making strides to better understand and treat PSC patients, with the ultimate goal of developing a cure for this disease.
Follow the PSC page and stay up-to-date as we post news about advances in PSC research, clinical trials, and available resources.
Cell free DNA (cfDNA) are degraded DNA fragments released to the blood stream during health and disease. This discovery was made more than 50 years ago. However, it was not until recently with the advent, scalability and affordability of next generation sequencing that cfDNA has become an approach to study biomarkers for disease [...]
In an abstract presented this week at the 2019 European Association for the Study of the Liver (EASL) meeting in Vienna, Austria, Dr. John Eaton from Mayo Clinic, Rochester, MN, reported the confirmation of the PREsTo machine learning algorithm for the prognostication of disease progression in a randomized trial [...]
We are privileged to host in Rochester, Minnesota the 15th annual conference for PSC patients and their caregivers (June 20-23, 2019). In a partnership with the PSC Partners Seeking a Cure we have created an exciting and informative program (please see the attached agenda). During this conference, we will highlight our current state of-the-art research efforts, and [...]
In the early 1980s, Ravi Iyer, Ph.D., helped usher in a new application of artificial intelligence, one marked by the ability to predict when individual machines would fail. At the time, computer scientists had developed systems allowing machines to perform tasks normally requiring human intelligence, such as speech recognition [...]
This Thursday, February 28th, we celebrate: "Rare Disease Day". Therefore, we dedicate this week's post to the anniversary of Rare Disease Day in an effort to raise awareness about rare diseases.
Rare diseases are individually rare but collectively common. In the United States, a “rare disease” is defined [...]