Research Opportunity: Non-invasive brain stimulation for MCI and depression

Hello!  As you may know, HABIT has grown beyond just Mayo Clinic to include other institutions that either offer HABIT as a clinical intervention or centers that collaborate with us on research.  One of these sites is the Medical University of South Carolina (MUSC) in Charleston.  While the following study is not a HABIT study, the group at MUSC is doing such interesting work that we thought we'd pass this study opportunity along.

From our colleagues at MUSC:

A clinical trial is testing whether non-invasive brain stimulation, Transcranial Magnetic Stimulation (TMS), can be used to treat the symptoms of mild cognitive impairment (MCI)and depression. TMS uses a magnetic field to stimulate specific areas of the brain that support memory, thinking skills, and mood. Our hope is that we can use TMS to PUSH against memory decline and depression.

TMS is an FDA-approved treatment for depression and has been shown to be a promising treatment for several other conditions. In studies of TMS for depression, individuals have also experienced improved memory and thinking. Therefore, we think TMS might be a good treatment for people with MCI since it is common for people with this condition to experience a lower mood along with changes in their memory and thinking. However, we don't yet know how much TMS treatment is needed to improve these different symptoms. Therefore, the goal of this study is to determine the optimal dose of TMS treatment for symptoms of depression and memory and thinking skills in people with MCI.

If you are between the ages of 60 and 85 years old, have been diagnosed with mild cognitive impairment (MCI), and have depression, you could be eligible to participate in this clinical trial (NCT05992831) at the Medical University of South Carolina (MUSC) in Charleston, SC. You must also have a co-participant with whom you have at least weekly contact who can participate in a few of the study visits.

This study if sponsored by the National Institutes of Health (NIH). If you qualify for the study, you will be paid up to $645 for your participation. Travel reimbursement may be provided. The total time you will be in this study is about six months. We may do some visits over video, but most visits will require you to be in person. You will make approximately 10-12 visits to the Medical University of South Carolina for memory testing, brain MRIs, and TMS treatments.

Click here for more information or fill out the following survey: https://redcap.link/PUSH_2 and our team will be in touch.

Contact Us: Katrina Madden (843) 792-9186 PUSHstudy@musc.edu