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Cell free DNA (cfDNA) are degraded DNA fragments released to the blood stream during health and disease. This discovery was made more than 50 years ago. However, it was not until recently with the advent, scalability and affordability of next generation sequencing that cfDNA has become an approach to study biomarkers for disease progression. In our recent review on cfDNA, published in the "Therapeutic Advances in Gastroenterology", we discuss the principals, current advances and future applications about cfDNA technologies including their use in gastrointestinal and liver disease
The PDF of the published article can be found here.
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