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Comments (3,373)

It was about one month before I started feeling anything different on Orgovyx. Hot flashes started...

https://connect.mayoclinic.org/comment/1508620/

Discussion: Starting Orgovyx - how long for side effects to occur?

Support Group: Prostate Cancer

Posted: Feb 18 7:57am

@jeffmark - Doc has been preparing me for upcoming Rad Therapy with meds Orgovyx and Nubeqa....

https://connect.mayoclinic.org/comment/1536173/

Discussion: Navigating Biologics by McKesson for D and mail-order 90-day Orgovyx

Support Group: Prostate Cancer

Posted: 5 days ago

Try Orgovyx, studies have shown there is no large difference between surgical and medical castration except...

https://connect.mayoclinic.org/comment/1514281/

Discussion: Anyone considered bilateral orchiectomy: Why or why not?

Support Group: Prostate Cancer

Posted: Feb 25 9:55am

Sorry slight correction. My brother is on Lupron NOT Orgovyx.

https://connect.mayoclinic.org/comment/921895/

Discussion: Rising PSA number from 5.7 at Biopsy to 6.7 in 4 months with Gleason 6

Support Group: Prostate Cancer

Posted: Aug 31, 2023

are you suggesting I should stay on Orgovyx for now?

https://connect.mayoclinic.org/comment/1186410/

Discussion: Dr Mark Scholz/PCRI

Support Group: Prostate Cancer

Posted: Dec 7, 2024

What was your T immediately before starting Orgovyx?

https://connect.mayoclinic.org/comment/1151875/

Discussion: Orgovyx and the timeline for return of normal testosterone level

Support Group: Prostate Cancer

Posted: Oct 4, 2024

Statistics...mean, mode, average, standard deviation... My recovery of T with the 18th months of Lupron was...

https://connect.mayoclinic.org/comment/1321321/

Discussion: How long after Lupron will testosterone level return to normal?

Support Group: Prostate Cancer

Posted: Jun 6, 2025

With your testosterone that low fatigue is a major issue. The tiredness in your legs is...

https://connect.mayoclinic.org/comment/1152895/

Discussion: Leg Issues Long After Radiation and ADT

Support Group: Prostate Cancer

Posted: Oct 6, 2024

GnRH: Gonadotropin Releasing Hormone Antagonists of GnRH: LUPRON [ELIGARD], (leuprolide) ORGOVYX, (relugolix) An advantage of ORGOVYX...

https://connect.mayoclinic.org/comment/1423025/

Discussion: Lupron v. orgovyx...which is preferable for the heart?

Support Group: Prostate Cancer

Posted: Oct 25, 2025

I am sorry you're experiencing many side effects listed by the Orgovyx manufacturer. My 6 months...

https://connect.mayoclinic.org/comment/1371780/

Discussion: In praise of Orgovyx

Support Group: Prostate Cancer

Posted: Aug 16, 2025

I had Stage 4a, Gleason 9 and Decipher .99. I had prostatectomy then started Orgovyx 1...

https://connect.mayoclinic.org/comment/1353911/

Discussion: Being treated for Gleason 9

Support Group: Prostate Cancer

Posted: Jul 22, 2025

I had fewer mental health issues about 45 days after I switched from monthly Lutron to...

https://connect.mayoclinic.org/comment/1155118/

Discussion: Looking for feedback - Lupron vs Orgovyx

Support Group: Prostate Cancer

Posted: Oct 10, 2024

How long ago did you stop Orgovyx?

https://connect.mayoclinic.org/comment/1327880/

Discussion: Gleason 9: ADT before radiation

Support Group: Prostate Cancer

Posted: Jun 15, 2025

@bryanta I was on Lupron for six years. And then Orgovyx for one more. I stopped...

https://connect.mayoclinic.org/comment/1431783/

Discussion: Unable to find cause of symptoms from prostate treatment or TBE

Support Group: Prostate Cancer

Posted: Nov 5, 2025

Gleason 7, N1M0 initial PET eval indicated active Iliac nodes, surgical oncologist disagrees. 5mos .Orgovyx now...

https://connect.mayoclinic.org/comment/1307829/

Discussion: Taking Orgovyx long term

Support Group: Prostate Cancer

Posted: May 19, 2025

Orgovyx is basically the same thing as Firmagon — a GnRH antagonist — but in pill...

https://connect.mayoclinic.org/comment/1282752/

Discussion: ‘Big Guns’ - Triple Therapy with Double Chemo - How to prepare?

Support Group: Prostate Cancer

Posted: Apr 15, 2025

Anyone on Orgovyx that developed anemia? My Folate RBC is low.

https://connect.mayoclinic.org/comment/1330264/

Discussion: ADT, Brachytherapy, IMRT...done!

Support Group: Prostate Cancer

Posted: Jun 18, 2025

I've had sleep issues for a long time. Lupron and Orgovyx made it worse. I take...

https://connect.mayoclinic.org/comment/1531092/

Discussion: Problems with Sleeping on Orgovyx

Support Group: Prostate Cancer

Posted: Mar 20 6:17am

@michaelcharles, thank you for your response and frankness of how bad you found ADT to be....

https://connect.mayoclinic.org/comment/1528308/

Discussion: Should I add ADT to Salvage Radiation at age 76?

Support Group: Prostate Cancer

Posted: Mar 16 12:37pm

My husband has been on Orgovyx since October of 2021. He loves it as it is...

https://connect.mayoclinic.org/comment/817299/

Discussion: What's your experience with Orgovyx (relugolix)?

Support Group: Prostate Cancer

Posted: Feb 25, 2023

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