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Comments (3,505)

It was about one month before I started feeling anything different on Orgovyx. Hot flashes started...

https://connect.mayoclinic.org/comment/1508620/

Discussion: Starting Orgovyx - how long for side effects to occur?

Support Group: Prostate Cancer

Posted: Feb 18 7:57am

If ADT lasts less than 2 months just keep up with the exercise (fight through any...

https://connect.mayoclinic.org/comment/1529381/

Discussion: Hormone therapy before radiation treatment question....

Support Group: Prostate Cancer

Posted: Mar 17 6:25pm

Sorry slight correction. My brother is on Lupron NOT Orgovyx.

https://connect.mayoclinic.org/comment/921895/

Discussion: Rising PSA number from 5.7 at Biopsy to 6.7 in 4 months with Gleason 6

Support Group: Prostate Cancer

Posted: Aug 31, 2023

are you suggesting I should stay on Orgovyx for now?

https://connect.mayoclinic.org/comment/1186410/

Discussion: Dr Mark Scholz/PCRI

Support Group: Prostate Cancer

Posted: Dec 7, 2024

Along with your Orgovyx did they also have you try adding abiraterone or one of the...

https://connect.mayoclinic.org/comment/1330128/

Discussion: Stopping ADT Scared and Anxiety Update

Support Group: Prostate Cancer

Posted: Jun 18, 2025

@beachguy Were you favorable intermediate risk? I was unfavorable intermediate, that's why my radiation oncologist started...

https://connect.mayoclinic.org/comment/1448957/

Discussion: What PSA to expect 2-3 months after ending Radiation?

Support Group: Prostate Cancer

Posted: Nov 28, 2025

Most days, walking is an effort from ORGOVYX related joint pain after only 45 days! Having...

https://connect.mayoclinic.org/comment/1124944/

Discussion: ADT/ ORGOVYX Day 45; Told Radiation Is Next

Support Group: Prostate Cancer

Posted: Aug 16, 2024

I had Stage 4a, Gleason 9 and Decipher .99. I had prostatectomy then started Orgovyx 1...

https://connect.mayoclinic.org/comment/1353911/

Discussion: Being treated for Gleason 9

Support Group: Prostate Cancer

Posted: Jul 22, 2025

I had fewer mental health issues about 45 days after I switched from monthly Lutron to...

https://connect.mayoclinic.org/comment/1155118/

Discussion: Looking for feedback - Lupron vs Orgovyx

Support Group: Prostate Cancer

Posted: Oct 10, 2024

Statistics...mean, mode, average, standard deviation... My recovery of T with the 18th months of Lupron was...

https://connect.mayoclinic.org/comment/1321321/

Discussion: How long after Lupron will testosterone level return to normal?

Support Group: Prostate Cancer

Posted: Jun 6, 2025

With your testosterone that low fatigue is a major issue. The tiredness in your legs is...

https://connect.mayoclinic.org/comment/1152895/

Discussion: Leg Issues Long After Radiation and ADT

Support Group: Prostate Cancer

Posted: Oct 6, 2024

What was your T immediately before starting Orgovyx?

https://connect.mayoclinic.org/comment/1151875/

Discussion: Orgovyx and the timeline for return of normal testosterone level

Support Group: Prostate Cancer

Posted: Oct 4, 2024

@denis76 Which country are you in, Denis? Here in Canada, Orgovyx is available, but many oncologists...

https://connect.mayoclinic.org/comment/1536090/

Discussion: Urologist said I could stop Orgovyx. Your thoughts?

Support Group: Prostate Cancer

Posted: Mar 26 6:07pm

Thanks for your motivational response. Yes the plan is to have radiation after some time on...

https://connect.mayoclinic.org/comment/1391906/

Discussion: How fast does Orgovyx work to reduce PSA?

Support Group: Prostate Cancer

Posted: Sep 11, 2025

My husband has been on Orgovyx since October of 2021. He loves it as it is...

https://connect.mayoclinic.org/comment/817299/

Discussion: What's your experience with Orgovyx (relugolix)?

Support Group: Prostate Cancer

Posted: Feb 25, 2023

Yes. Firmagon for the first 2½ years, then Orgovyx (basically Firmagon in pill form) for the...

https://connect.mayoclinic.org/comment/1333901/

Discussion: Adding a second medicine question

Support Group: Prostate Cancer

Posted: Jun 24, 2025

Why not just try it? Taking it for a short period does no permanent damage, &...

https://connect.mayoclinic.org/comment/1556017/

Discussion: Prostate cancer metastacized to the Iliac lymph node

Support Group: Prostate Cancer

Posted: 6 days ago

GnRH: Gonadotropin Releasing Hormone Antagonists of GnRH: LUPRON [ELIGARD], (leuprolide) ORGOVYX, (relugolix) An advantage of ORGOVYX...

https://connect.mayoclinic.org/comment/1423025/

Discussion: Lupron v. orgovyx...which is preferable for the heart?

Support Group: Prostate Cancer

Posted: Oct 25, 2025

I am sorry you're experiencing many side effects listed by the Orgovyx manufacturer. My 6 months...

https://connect.mayoclinic.org/comment/1371780/

Discussion: In praise of Orgovyx

Support Group: Prostate Cancer

Posted: Aug 16, 2025

@bryanta I was on Lupron for six years. And then Orgovyx for one more. I stopped...

https://connect.mayoclinic.org/comment/1431783/

Discussion: Unable to find cause of symptoms from prostate treatment or TBE

Support Group: Prostate Cancer

Posted: Nov 5, 2025

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