Y-90 liver cancer treatment: What's your experience?

My husband has Cholangiosarcoma and had the Y90 on the 17th of June. He has had so much pain since. He hasn't ate it's terrible to see him go through this. We are trying to get a hold of his Dr now because we think something may be wrong considering it's been 3 weeks

I had the Y90 procedure a year ago for single tumor 4 cm HCC. No pain or complications.

My AFP tumor marker went from 799 to 6 in a year and cancer or tumor is non detectable. I still show a lot of radiation but to date docs aren’t too concerned. Being monitored every three months with labs and imaging.

Currently at Mayo Clinic for liver transplant evaluation - praying it goes well.

I had an amazing IR doctor and had no pain following the procedure on Jan 31, 2025. I have had one CT in May which showed some necrosis & an MRI is scheduled for late July. My NET specialist said that 6 mos should show the full effect of the Y90. BTW, the mapping procedure was done prior to the Y90 as a test to be sure my tumor was receptive to the radiation beads.

I had liver cancer and had what you are calling y90 treatment. It took two treatments to stop the cancer, which also drove me higher on the transplant list (I had NAFL and Cirrhosis).
The treatment for me was painful after with compression at the injection spot

What is mapping you guys talk about? I just had CT scan and then the treatment.

@jam62, you may also wish to follow the Transplants support group here: https://connect.mayoclinic.org/group/transplants/

You might be interested in this related discussion:
- Anyone waiting for liver transplant and diagnosed with liver cancer? https://connect.mayoclinic.org/discussion/liver-transplant-6/

See all https://connect.mayoclinic.org/search/discussions/?search=liver%20cancer%20and%20transplant

@fm4 and @jam62, how did your first Y90 treatments go?

I have liver cancer too. They already did the mapping I’m scheduled for the NY 90 at the end of this month. I’m a little nervous. I just hope it works.

I have nonalcoholic cirrhosis and liver cancer. I had Y90 mapping procedure a couple of weeks ago with Y90 procedure scheduled for next week. Mapping was not bad at all except for laying flat for a couple of hours afterwards. Ready to get the radiation beads inserted to start shrinking my 4 cm tumor. I am already on the liver transplant waitlist.

Thank you. I will talk to my deratologist.

My husband got relief with light therapy, prescribed by a dermatologist after topical creams and lotions didn't take care of it. It's non-invasive, highly controlled exposure to, I think, UV-A and B rays. He had it twice a week, and after a few months the itching was gone. (I had the same treatment for a skin condition not related to cancer. It worked, after nothing had for 4-5 years). It's worth asking about.

My IR physician told me she didn’t expect me to need her again after my Y90. It has been 2 weeks & my CT scan is not until May. I am feeling good except for fatigue & rest when I need to.